Results 91 to 100 of about 139,262 (370)

FasL Expression in Articular Discs of Human Temporomandibular Joint and Association with Osteoarthrosis [PDF]

, 2013
Background Apoptosis is a programme of cell death which does not induce an inflammatory response. Recent previous research has suggested a correlation between temporomandibular internal derangement and apoptosis.
Alanis, Luciana Reis Azevedo, Almeida, Luis Eduardo, Ambros, Viviane, Azevedo, Marina, Camejo, Flavio de Alcantara, Caporal, Karina Sao Thiago, Doetzer, Andrea, Noronha, Lucia, Olandoski, Marcia, Trevilatto, Paula C.   +9 more
core   +2 more sources

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

Environmental high temperature (heat stroke) causes articular cartilage damage in vivo and in vitro

Ecotoxicology and Environmental Safety
Heatstroke (HS) is gradually becoming a major challenge in the field of global public health with the trend of global warming. In recent years, extreme high-temperature weather events have occurred frequently in the world, which directly led to a ...
Sun yingfei, Yang feng, Ma haoning
doaj   +1 more source

Molecular characterization of articular cartilage from young adults with femoroacetabular impingement [PDF]

, 2013
BACKGROUND: Femoroacetabular impingement is a frequent cause of hip pain and may lead to secondary osteoarthritis, yet little is known about the molecular events linking mechanical hip impingement and articular cartilage degeneration.
Clohisy, John C., Gill, Corey S., Hashimoto, Shingo, Rai, Muhammad Farooq, Sandell, Linda J., Zhang, Zhiqi   +5 more
core   +2 more sources

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

The use of equine chondrogenic‐induced mesenchymal stem cells as a treatment for osteoarthritis : a randomised, double‐blinded, placebo‐controlled proof‐of‐concept study [PDF]

, 2019
Background: There is a need to improve therapies for osteoarthritis in horses. Objectives To assess the efficacy of equine allogeneic chondrogenic-induced mesenchymal stem cells combined with equine allogeneic plasma as a novel therapy for osteoarthritis
Bertone, AL, Broeckx, Sarah, Chiers, Koen, Duchateau, Luc, Dumoulin, Michèle, Hussein, H, Martens, Ann, Oosterlinck, Maarten, Pille, Frederik, Spaas, JH, Van Brantegem, Leen, Van Hecke, L   +11 more
core   +1 more source

Editorial Commentary: In Terms of Hip Arthroscopy Long-term Outcomes, Intra-articular Cartilage Damage Is More Important Than Hip Labral Treatment Method: The Second Habit of Highly Effective Surgeons [PDF]

, 2023
Itay Ron, Mitch Yelton, Jacob Shapira
openalex   +1 more source

Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang, Jianbo Huang, Shuwei Zhang, Sujiao Cao, Fangxue Du, Liqiang Zhou, Li Qiu, Yuanjiao Tang   +7 more
wiley   +1 more source

Intra-articular injection of mesenchymal stem cells leads to reduced inflammation and cartilage damage in murine antigen-induced arthritis

Journal of Translational Medicine, 2014
Rheumatoid arthritis (RA) is a debilitating and painful disease leading to increased morbidity and mortality and novel therapeutic approaches are needed.
O. Kehoe, Alison J. Cartwright, A. Askari, A. E. El Haj, J. Middleton   +4 more
semanticscholar   +1 more source

Bioprinting of Microtissues Within Mechanically Tunable Support Baths to Engineer Anisotropic Musculoskeletal Tissues

Advanced Science, EarlyView.
This study presents a novel 4D bioprinting platform for engineering biomimetic musculoskeletal grafts. By tuning the mechanical properties of support baths, we enhance tissue fusion, collagen alignment, and cell differentiation. Using this strategy, we successfully fabricate scaled‐up, anisotropic tissues such as meniscus, articular cartilage, and ...
Francesca D. Spagnuolo, Gabriela S. Kronemberger, Daniel J. Kelly   +2 more
wiley   +1 more source