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Imaging of articular cartilage

Indian Journal of Radiology and Imaging, 2014
We tried to review the role of magnetic resonance imaging (MRI) in understanding microscopic and morphologic structure of the articular cartilage. The optimal protocols and available spin-echo sequences in present day practice are reviewed in context of ...
Bhawan K Paunipagar, DD Rasalkar
doaj   +3 more sources

Assessment of morphology, radiopacity gradient and mechanical properties of articular cartilage with contrast-enhanced high-resolution peripheral quantitative computed tomography [PDF]

Frontiers in Bioengineering and Biotechnology
IntroductionDegenerative alterations in proteoglycans content and collagen structure compromise the mechanical integrity of articular cartilage and, therefore, its viscoelastic properties. Early detection of these subtle alterations is a prerequisite for
Simone Fantoni, Matteo Berni, Roberta Fognani, Giulia Fraterrigo, Paolo Cardarelli, Fabio Baruffaldi, Massimiliano Baleani   +6 more
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Comparison between articular chondrocytes and mesenchymal stromal cells for the production of articular cartilage implants

Frontiers in Bioengineering and Biotechnology, 2023
Focal lesions of articular cartilage give rise to pain and reduced joint function and may, if left untreated, lead to osteoarthritis. Implantation of in vitro generated, scaffold-free autologous cartilage discs may represent the best treatment option ...
Nadine Frerker, Tommy A. Karlsen, Maria Stensland, Tuula A. Nyman, Tuula A. Nyman, Simon Rayner, Simon Rayner, Simon Rayner, Jan E. Brinchmann, Jan E. Brinchmann   +9 more
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THE PERMEABILITY OF ARTICULAR CARTILAGE [PDF]

The Journal of Bone and Joint Surgery. British volume, 1968
1. We have shown that the permeability of cartilage is the same in necropsy specimens as in the living animal. We have concluded that studies of material transport into cartilage carried out on necropsy specimens validly reflect in vivo conditions. 2. We have studied the effect of agitation of the fluid in which cartilage is immersed upon the rate of
A, Maroudas, P, Bullough, S A, Swanson, M A, Freeman   +3 more
openaire   +2 more sources

Vitrification of particulated articular cartilage via calculated protocols

npj Regenerative Medicine, 2021
Preserving viable articular cartilage is a promising approach to address the shortage of graft tissue and enable the clinical repair of articular cartilage defects in articulating joints, such as the knee, ankle, and hip.
Kezhou Wu, Nadia Shardt, Leila Laouar, Janet A. W. Elliott, Nadr M. Jomha   +4 more
doaj   +1 more source

Acellular cartilage matrix biomimetic scaffold with immediate enrichment of autologous bone marrow mononuclear cells to repair articular cartilage defects

Materials Today Bio, 2022
Functional repair of articular cartilage defects is always a great challenge in joint surgery clinically. Tissue engineering strategies that combine autologous cell implantation with three-dimensional scaffolds have proven effective for repairing ...
Litao Jia, Peiling Zhang, Zheng Ci, Xiaoyan Hao, Baoshuai Bai, Wei Zhang, Haiyue Jiang, Guangdong Zhou   +7 more
doaj   +1 more source

CCN family member 2/connective tissue growth factor (CCN2/CTGF) has anti-aging effects that protect articular cartilage from age-related degenerative changes. [PDF]

PLoS ONE, 2013
To examine the role of connective tissue growth factor CCN2/CTGF (CCN2) in the maintenance of the articular cartilaginous phenotype, we analyzed knee joints from aging transgenic mice (TG) overexpressing CCN2 driven by the Col2a1 promoter.
Shinsuke Itoh, Takako Hattori, Nao Tomita, Eriko Aoyama, Yasutaka Yutani, Takashi Yamashiro, Masaharu Takigawa   +6 more
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The synovial microenvironment suppresses chondrocyte hypertrophy and promotes articular chondrocyte differentiation

npj Regenerative Medicine, 2022
During the development of the appendicular skeleton, the cartilaginous templates undergo hypertrophic differentiation and remodels into bone, except for the cartilage most adjacent to joint cavities where hypertrophic differentiation and endochondral ...
Michael Chau, Zelong Dou, Marta Baroncelli, Ellie B. Landman, Ameya Bendre, Masaru Kanekiyo, Alexandra Gkourogianni, Kevin Barnes, Lars Ottosson, Ola Nilsson   +9 more
doaj   +1 more source

Atomic Force Microscopy Micro-Indentation Methods for Determining the Elastic Modulus of Murine Articular Cartilage

Sensors, 2023
The mechanical properties of biological tissues influence their function and can predict degenerative conditions before gross histological or physiological changes are detectable. This is especially true for structural tissues such as articular cartilage,
Katherine M. Arnold, Delphine Sicard, Daniel J. Tschumperlin, Jennifer J. Westendorf   +3 more
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Effects of Articular Cartilage Constituents on Phosphotungstic Acid Enhanced Micro-Computed Tomography.

PLoS ONE, 2017
Contrast-enhanced micro-computed tomography (CEμCT) with phosphotungstic acid (PTA) has shown potential for detecting collagen distribution of articular cartilage.
Sakari S Karhula, Mikko A Finnilä, Mikko J Lammi, Janne H Ylärinne, Sami Kauppinen, Lassi Rieppo, Kenneth P H Pritzker, Heikki J Nieminen, Simo Saarakkala   +8 more
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