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Computational Models of Articular Cartilage [PDF]
In osteoarthritis, articular cartilage degenerates and eventually wears out, resulting in pain and disability. It is a major challenge in health care to prevent osteoarthritis or slow down the progression of the disease. The onset of osteoarthritis may result from an altered stress and strain state in cartilage, for example, due to an injury of ...
Rami K. Korhonen +3 more
openaire +3 more sources
Cryopreservation of articular cartilage
Cryopreservation has numerous practical applications in medicine, biotechnology, agriculture, forestry, aquaculture and biodiversity conservation, with huge potentials for biological cell and tissue banking. A specific tissue of interest for cryopreservation is the articular cartilage of the human knee joint for two major reasons: (1) clinically, there
Abazari, Alireza +3 more
openaire +2 more sources
Postnatal development of depth-dependent collagen density in ovine articular cartilage [PDF]
Articular cartilage (AC) is the layer of tissue that covers the articulating ends of the bones in diarthrodial joints. Adult AC is characterised by a depth-dependent composition and structure of the extracellular matrix that results in depth-dependent ...
Kranenbarg, S. +24 more
core +1 more source
The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated ...
Yoshitoshi Higuchi +10 more
doaj +1 more source
Response of human engineered cartilage based on articular or nasal chondrocytes to interleukin-1? and low oxygen [PDF]
Previous studies showed that human nasal chondrocytes (HNC) exhibit higher proliferation and chondrogenic capacity as compared to human articular chondrocytes (HAC).
Sylvie Miot +20 more
core +1 more source
Joint diseases that mainly lead to articular cartilage injury with prolonged severe pain as well as dysfunction have remained unexplained for many years.
Xu Han +4 more
doaj +1 more source
Freeze-thaw treatment effects on the dynamic mechanical properties of articular cartilage.
BACKGROUND: As a relatively non-regenerative tissue, articular cartilage has been targeted for cryopreservation as a method of mitigating a lack of donor tissue availability for transplant surgeries.
Szarko Matthew +11 more
core +1 more source
Dynamic stiffness of articular cartilage and potential repair materials [PDF]
Cartilage has limited potential for self repair. Therefore, articular cartilage lesions often lead to early osteoarthritis. Early clinical results of cartilage replacement procedures such as autologous matrix-induced chondrogenesis (AMIC) seem promising,
Ronken, Sarah
core +1 more source
Key roles of the superficial zone in articular cartilage physiology, pathology, and regeneration
. The superficial zone (SFZ) of articular cartilage is an important interface that isolates deeper zones from the microenvironment of the articular cavity and is directly exposed to various biological and mechanical stimuli. The SFZ is not only a crucial
Li Guo +4 more
doaj +1 more source
Purpose: To establish normative values for articular cartilage thickness in pediatric and adolescent knees using magnetic resonance imaging (MRI) and investigate for any associations with age and skeletal maturity.
Sreetha Sidharthan, M.D. +6 more
doaj +1 more source

