Results 21 to 30 of about 293,921 (283)
Scientific Reports, 2021 Articular cartilage is built by chondrocytes which become less active with age. This declining function of the chondrocytes, together with the avascular nature of the cartilage, impedes the spontaneous healing of chondral injuries.
Alexandre Dufour +10 more
doaj +1 more source
Freeze-thaw treatment effects on the dynamic mechanical properties of articular cartilage. [PDF]
, 2010 BACKGROUND: As a relatively non-regenerative tissue, articular cartilage has been targeted for cryopreservation as a method of mitigating a lack of donor tissue availability for transplant surgeries.
Szarko Matthew +11 more
core +2 more sources
Depletion of chondrocyte primary cilia reduces the compressive modulus of articular cartilage [PDF]
, 2014 Primary cilia are slender, microtubule based structures found in the majority of cell types with one cilium per cell. In articular cartilage, primary cilia are required for chondrocyte mechanotransduction and the development of healthy tissue.
Ramaswamy, G +7 more
core +1 more source
Direct Visualisation of the Depth-Dependent Mechanical Properties of Full-Thickness Articular Cartilage. [PDF]
, 2012 The structural anisotropy of articular cartilage controls its deformation response. As proteoglycans and collagen vary with depth, simple uniaxial compression results in inhomogeneous deformation with distinct depth-dependent mechanical properties ...
Szarko, M, Xia, Y
core +1 more source
Differential gene expression associated with postnatal equine articular cartilage maturation
BMC Musculoskeletal Disorders, 2008 Background Articular cartilage undergoes an important maturation process from neonate to adult that is reflected by alterations in matrix protein organization and increased heterogeneity of chondrocyte morphology.
Stromberg Arnold J +3 more
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A review of the differences between normal and osteoarthritis articular cartilage in human knee and ankle joints [PDF]
, 2009 Background: Osteoarthritis (OA) is the most common joint disease yet its pathophysiology is still poorly understood. It is more prevalent in some lower limb joints than others; in particular the knee is more commonly affected than the ankle.
Beeson, Paul +2 more
core +1 more source
Cryopreservation of articular cartilage
Cryobiology, 2013 Cryopreservation has numerous practical applications in medicine, biotechnology, agriculture, forestry, aquaculture and biodiversity conservation, with huge potentials for biological cell and tissue banking. A specific tissue of interest for cryopreservation is the articular cartilage of the human knee joint for two major reasons: (1) clinically, there
Abazari, Alireza +3 more
openaire +2 more sources
Computational Models of Articular Cartilage [PDF]
Computational and Mathematical Methods in Medicine, 2013 In osteoarthritis, articular cartilage degenerates and eventually wears out, resulting in pain and disability. It is a major challenge in health care to prevent osteoarthritis or slow down the progression of the disease. The onset of osteoarthritis may result from an altered stress and strain state in cartilage, for example, due to an injury of ...
Rami K. Korhonen +3 more
openaire +3 more sources
Scientific Reports, 2017 The catabolism of hyaluronan in articular cartilage remains unclear. The aims of this study were to investigate the effects of hyaluronidase 2 (Hyal2) knockdown in articular cartilage on the development of osteoarthritis (OA) using genetic manipulated ...
Yoshitoshi Higuchi +10 more
doaj +1 more source
Arthroscopy, Sports Medicine, and Rehabilitation, 2021 Purpose: To establish normative values for articular cartilage thickness in pediatric and adolescent knees using magnetic resonance imaging (MRI) and investigate for any associations with age and skeletal maturity.
Sreetha Sidharthan, M.D. +6 more
doaj +1 more source