Results 101 to 110 of about 139,262 (370)
Bioresources and BioprocessingOsteoarthritis (OA) of the knee is a common degenerative articular disorder and is one of the main causes of pain and functional disability. Cartilage damage is frequently linked to elevated osteoarthritis incidence.
Srinivasan Periasamy +3 more
doaj +1 more source
Outerbridge grade IV cartilage lesions in the hip identified at arthroscopy [PDF]
, 2017 No abstract ...
McLean, Michael +2 more
core +1 more source
Advanced Science, EarlyView.FSTL1 promotes glycolysis during chondrocyte fibrosis by triggering the HIF‐1 signaling pathway, which causes lactate to accumulate. The buildup of lactate leads to changes in histone lysine lactylation, which in turn enhances the expression of genes associated with fibrosis.
Feng Lu +12 more
wiley +1 more source
Histopathological Changes of Applying Nano-Fat on Articular Cartilage Degenerative Defect in A Dog Model [PDF]
Basrah Journal of Veterinary ResearchDamage to articular cartilage can ultimately lead to osteoarthritis, a debilitating degenerative joint disease. Treating cartilage damage is difficult because cartilage has a limited ability to heal itself and because currently available treatments are ...
Ali Abokhamsen, bassim khashjoori
doaj +1 more source
A Measure of Control for Secondary Cytokine-Induced Injury of Articular Cartilage: A Computational Study [PDF]
, 2013 In previous works, the author and collaborators establish a mathematical model for injury response in articular cartilage. In this paper we use mathematical software and computational techniques, applied to an existing model to explore in more detail how
Graham, Jason M
core
c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases. [PDF]
, 2012 The c-Jun N-terminal kinases (JNKs) are members of the mitogen-activated protein kinase (MAPK) family and are activated by environmental stress. JNK is also activated by proinflammatory cytokines, such as TNF and IL-1, and Toll-like receptor ligands ...
Firestein, Gary S, Guma, Monica
core +1 more source
T-2 toxin induces articular cartilage damage by increasing the expression of MMP-13 via the TGF-β receptor pathway [PDF]
, 2022 Ying Zhang +5 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan +16 more
wiley +1 more source
Modeling and Simulation of the Effects of Cyclic Loading on Articular Cartilage Lesion Formation
, 2013 We present a model of articular cartilage lesion formation to simulate the effects of cyclic loading. This model extends and modifies the reaction-diffusion-delay model by Graham et al.
Ayati, Bruce P. +5 more
core
Spectrum of arthroscopic findings in 84 canine elbow joints diagnosed with medial compartment erosion [PDF]
, 2018 Elbow dysplasia is an important cause of forelimb lameness in large breed dogs. The aim of this study was to report on the arthroscopic findings associated with medial compartment erosion (MCE) of the canine elbow joint.
Broeckx, Bart +6 more
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