Results 131 to 140 of about 139,262 (370)

Strategic Design and Fabrication of Engineered Scaffolds for Articular Cartilage Repair

open access: yesJournal of Functional Biomaterials, 2012
Damage to articular cartilage can eventually lead to osteoarthritis (OA), a debilitating, degenerative joint disease that affects millions of people around the world.
Xiongbiao Chen   +2 more
doaj   +1 more source

Semi‐autonomous Navigation of Magnetic Microcarriers for Knee Cartilage Regeneration

open access: yesAdvanced Intelligent Systems, EarlyView.
Autonomous navigation of magnetic microcarriers in complex 3D environments is investigated through a semi‐autonomous strategy integrating magnetic actuation with monocular visual feedback. Real‐time global tracking is achieved via radio‐frequency‐based localization and depth estimation, while model‐based computation determines optimal steering forces ...
Kim Tien Nguyen   +3 more
wiley   +1 more source

Assessment of Articular Cartilage by Second Harmonic Microscopy: Challenges and Opportunities

open access: yesFrontiers in Physics, 2019
Second harmonic microscopy (SHM) has emerged as a powerful non-destructive optical imaging modality that has high potential to perform the advanced structural characterization of intact articular cartilage.
Rajesh Kumar, Anup Kumar
doaj   +1 more source

Time‐ and dose‐related pathological changes in knee osteoarthritis rat model induced by monosodium iodoacetate

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Time‐ and dose‐related pathological changes of knee osteoarthritis rat model induced by monosodium iodoacetate. Abstract Knee osteoarthritis (KOA) is a chronic degenerative disease. Monosodium iodoacetate (MIA) induction is the most commonly used therapeutic effect evaluation and mechanism of action research model; we observed a lack of standardization
Wei Pu   +6 more
wiley   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

open access: yesAdvanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai   +7 more
wiley   +1 more source

Decoding the Pathophysiology of Autoimmune Diseases—Mechanism, Triggers, and Nanotherapeutics: A Review

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review highlights how autoimmune diseases arise from intertwined immunological, genetic, and environmental factors, emphasizing gut microbiota dysbiosis as a pivotal driver. It outlines emerging nanotechnology‐based strategies—such as liposomes, hydrogels, and polymeric nanoparticles—that enhance targeted drug delivery, minimize systemic toxicity,
Md. Meraj Ansari   +5 more
wiley   +1 more source

Hypothalamus Regulates Anabolic Metabolism of Articular Cartilage Superficial Chondrocytes through PGE2 Skeletal Interoception

open access: yesAdvanced Science
Degeneration of articular cartilage is the key underlying cause of most joint‐related diseases and yet little is known about its regeneration. Here, we report that skeletal interoception induces anabolic synthesis of superficial membrane by tuning down ...
Ziyi Wang   +8 more
doaj   +1 more source

Histochemistry as a unique approach for investigating normal and osteoarthritic cartilage

open access: yesEuropean Journal of Histochemistry, 2014
In this review article, we describe benefits and disadvantages of the established histochemical methods for studying articular cartilage tissue under normal, pathological and experimental conditions.
G. Musumeci   +5 more
doaj   +1 more source

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