Results 311 to 320 of about 139,262 (370)

Hip morphology influences the pattern of articular cartilage damage

Knee Surgery, Sports Traumatology, Arthroscopy, 2014
AbstractPurposeThe aim of this study was to obtain data on chondral damage and compare the damage patterns of various hip disorders.MethodsData were collected at 100 consecutive arthroscopies, and chondral lesions were recorded on anatomic articular maps divided into different anatomical zones.
Mitsunori, Kaya, Tomoyuki, Suzuki, Makoto, Emori, Toshihiko, Yamashita   +3 more
openaire   +3 more sources

On mechanical mechanism of damage evolution in articular cartilage

Materials Science and Engineering: C, 2017
Superficial lesions of cartilage are the direct indication of osteoarthritis. To investigate the mechanical mechanism of cartilage with micro-defect under external loading, a new plain strain numerical model with micro-defect was proposed and damage evolution progression in cartilage over time has been simulated, the parameter were studied including ...
Yu-Tao, Men, Yan-Long, Jiang, Ling, Chen, Chun-Qiu, Zhang, Jin-Duo, Ye   +4 more
openaire   +3 more sources

Meniscal tears and articular cartilage damage in the dislocated knee

Knee Surgery, Sports Traumatology, Arthroscopy, 2015
Knee dislocations can cause significant damage to intra-articular knee structures, but currently there are limited data reporting articular cartilage and meniscal injuries in this setting. The purpose of this study is to (1) report the rate of concomitant intra-articular injuries at the time of multiligament reconstruction for knee dislocation, (2 ...
Aaron J, Krych, Paul L, Sousa, Alexander H, King, William M, Engasser, Michael J, Stuart, Bruce A, Levy   +5 more
openaire   +3 more sources

A phenomenological mathematical model of the articular cartilage damage

Computer Methods and Programs in Biomedicine, 2011
Articular cartilage (AC) is a biological tissue that allows the distribution of mechanical loads and movement of joints. The presence of these mechanical loads influences the behavior and physiological condition of AC. The loads may cause damaged by fatigue through injuries due to repeated accumulated stresses.
N S, Landinez-Parra, D A, Garzón-Alvarado, J C, Vanegas-Acosta   +2 more
openaire   +3 more sources

Friction coefficients for mechanically damaged bovine articular cartilage

Biotechnology and Bioengineering, 2012
AbstractWe used a pin‐on‐disc tribometer to measure the friction coefficient of both pristine and mechanically damaged cartilage samples in the presence of different lubricant solutions. The experimental set up maximizes the lubrication mechanism due to interstitial fluid pressurization.
Liu, Shi, Daniel B, Brunski, Vassilios I, Sikavitsas, Matthew B, Johnson, Alberto, Striolo   +4 more
openaire   +2 more sources

Minocycline reduces articular cartilage damage following osteochondral injury

The Knee, 2012
Secondary injury pathways activated after chondral and osteochondral injury represent a potential target for therapies designed to minimize articular cartilage loss. The primary objective of this study was to test the potential chondroprotective effects of intra-articular minocycline following osteochondral injury.In vitro experiments were first ...
Akira, Yamamoto, Adam P, Warren, Hubert T, Kim   +2 more
openaire   +2 more sources

Long‐Term Recruitment of Endogenous M2 Macrophages by Platelet Lysate‐Rich Plasma Macroporous Hydrogel Scaffold for Articular Cartilage Defect Repair

Advanced Healthcare Materials, 2021
After cartilage damage, a large number of monocytes/macrophages infiltrate into adjacent synovium and the resident macrophages in synovial tissue transform to activated macrophages (M1), which secrete pro‐inflammatory cytokines to induce sustained ...
Xiaoyun Pan, Shan Yuan, Xiaojie Xun, Zhiyuan Fan, Xinghe Xue, Changhuan Zhang, Jilong Wang, Junjie Deng   +7 more
semanticscholar   +1 more source

Bisphosphonates rescue articular cartilage from trauma damage

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC), 2015
We previously found that systemic injection of zoledronic acid (ZA), a bisphosphonate, could suppress the post-traumatic osteoarthritis (PTOA) in meniscus dislocated animal model. The aim of this study is to explore the cellular and molecular mechanisms underlying ZA's chondro-protective function.
Yilu Zhou, Miri Park, Liyun Wang, X. Lucas Lu   +3 more
openaire   +1 more source

Active oxygen species, articular inflammation and cartilage damage

1992
Rheumatoid arthritis and osteoarthritis are age-related diseases, in which degenerative changes (arthrosis) and superimposed inflammatory reactions (arthritis) lead to progressive destruction of the joints. Active oxygen species derived from various sources play a role in this process, which may be influenced by appropriate treatment with antioxidants ...
Y, Henrotin, G, Deby-Dupont, C, Deby, P, Franchimont, I, Emerit   +4 more
openaire   +2 more sources