Results 111 to 120 of about 769,096 (329)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
The C/D Model and the Effect of Prosodic Structure on Articulation
LanguagesThe Converter/Distributor (C/D) model, as proposed by Fujimura is theoretically grounded on articulatory observations of X-ray microbeam (XRMB) data that show that utterance syllable prominence patterns “dictate” the size, timing and phrasing of ...
Donna Mae Erickson
doaj +1 more source
Analysis of Tonguing and Blowing Actions During Clarinet Performance
Frontiers in Psychology, 2018 Articulation on the clarinet is achieved by a combination of precise actions taking place inside the player's mouth. With the aim to analyse the effects of tonguing and blowing actions during playing, several physical variables are measured and ...
Montserrat Pàmies-Vilà +2 more
doaj +1 more source
Articulatory optimisation in perturbed vowel articulation [PDF]
, 2007 A two-week perturbation EMA-experiment was carried out with palatal prostheses. Articulatory effort for five speakers was assessed by means of peak acceleration and jerk during the tongue tip gestures from /t/ towards /i, e, o, y, u/.
Brunner, Jana +2 more
core +4 more sources
Learning weakly supervised multimodal phoneme embeddings
, 2017 Recent works have explored deep architectures for learning multimodal speech representation (e.g. audio and images, articulation and audio) in a supervised way. Here we investigate the role of combining different speech modalities, i.e.
Chaabouni, Rahma +3 more
core +3 more sources
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Modeling Dimensions of Prosodic Prominence
Frontiers in Communication, 2019 Detailed modifications both in the laryngeal as well as in the supra-laryngeal domain have been shown to be used by speakers of German to express prosodic prominence.
Simon Roessig, Doris Mücke
doaj +1 more source
Mechanical Engineering Design Project report: Enabler control systems [PDF]
The Controls Group was assigned the responsibility for designing the Enabler's control system. The requirement for the design was that the control system must provide a simple user interface to control the boom articulation joints, chassis articulation ...
Cullen, Christian +3 more
core +1 more source
Voice and speech functions (B310-B340) [PDF]
, 2012 The International Classification of Functioning, Disability and Health for Children and Youth (ICF-CY) domain ‘voice and speech functions’ (b3) includes production and quality of voice (b310), articulation functions (b320), fluency and rhythm of speech ...
McCartney, Elspeth
core
, 2016 Human infants can discover words directly from unsegmented speech signals without any explicitly labeled data. In this paper, we develop a novel machine learning method called nonparametric Bayesian double articulation analyzer (NPB-DAA) that can ...
Nagasaka, Shogo +2 more
core +1 more source