Results 91 to 100 of about 329,448 (411)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
, 2017 This chapter examines the essential role of knowledge articulation in enabling brokers to mobilize and coordinate others’ actions to get new things done.
David Obstfeld
core +1 more source
Frontiers in Psychology, 2020 Piano performance involves several levels of motor abundancy. Identification of kinematic strategies that enhance performance and reduce risks of practice-related musculoskeletal disorders (PRMD) represents an important research topic since more than ...
Felipe Verdugo +8 more
doaj +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Hanau Articulator Training: Zeroing the Articulator
MedEdPORTAL, 2010 Abstract This self-paced online module shows the parts of a standard Hanau articulator, teaches students how to reset it to zero in preparation for mounting casts, and allows students to zero a virtual Hanau articulator. This Flash-based module is an excellent preparation for learning this basic laboratory instrument before beginning laboratory and/or ...
Emily Springfield, Mauricio Moeller
openaire +2 more sources
Stuart Hall and the theory and practice of articulation
, 2015 In this article, I argue that the idea of articulation links three different dimensions of Stuart Hall's work: it is central to the work of cultural politics, to the work of hegemony and to his practice of embodied pedagogy.
J. Clarke
semanticscholar +1 more source
The Interplay between Place, Culture, and Ideology in Steinbeck’s The Grapes of Wrath: A Reading in the light of Cultural Materialism [PDF]
Al-Mağallah Al-ʿilmiyyaẗ Li Kulliyyaẗ Al-Adāb - Ǧāmiʿaẗ AsyūṭCultural materialism questions the modernist claims to timelessness and its tendency to set certain meanings as universal. Dealing with the particularity of incidents, cultural materialism introduces a type of cultural analysis that looks deeply into the
Alia Abbas M. Hassan Mabrouk
doaj +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Regional variation and articulation rate in French
J. Phonetics, 2015 The present investigation deals with regional variation and articulation rate in French. The articulation rate in read speech and in spontaneous speech was examined in seven variants of French: Paris and Lyon in France; Tournai and Liege in Belgium ...
S. Schwab, M. Avanzi
semanticscholar +1 more source