Results 71 to 80 of about 249,022 (295)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Spectrographs Speech Measures and Audiologic Findings of Young Children with Unilateral Cleft Lip and Palate

Turkish Journal of Orthodontics, 2008
The aim of the study was to assess the audiologic and the speech status of operated unilateral cleft preschooler patients who have no orthodontic, otologic, and speech therapy.
Fatih Ögüt, Gökhan Önçağ, Servet Doğan, Erkan Zeki Engin, M. Akif Kılıç   +4 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Using Modern Conducting Approaches in the Performance of Classical Repertoire

Studia Universitatis Babeş-Bolyai. Musica
The study aims to reveal the conducting techniques as a complex unified system. Its components are profoundly interconnected and have inherent functions, content and significance.
Vasyl CHUCHMAN, Anastasiia PATER, Vira NAIDA, Iryna PARFENTIEVA, Liubomyr MARTYNIV   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Publisher Correction: Effect of small heat release and viscosity on thermal-diffusive instability

Scientific Reports, 2021
Keigo Wada
doaj   +1 more source

THE ARTICULATION OF THE NOTES IN TREATIES DEDICATED TO WOODWIND INSTRUMENTS FROM THE BAROQUE ERA

Studia Universitatis Babeş-Bolyai. Musica, 2014
The articulations described in the treaties from the baroque era give proof to a wider variety, compared to the ones used in our days. The knowledge and application of these types of articulations offers a possibility to spread and enrich the expression
Ignác Csaba FILIP
doaj  

Knowledge articulation

, 2013
Knowledge articulation involves the conversion or extraction of tacit knowledge from individuals into explicit and more generic knowledge through collective efforts.
Tell, Fredrik,
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Communication disorders in individuals with cleft lip and palate: An overview

Indian Journal of Plastic Surgery, 2009
The need for an interdisciplinary approach in the comprehensive management of individuals with cleft lip and palate is well recognized. This article provides an introduction to communication disorders in individuals with cleft lip and palate for members ...
Roopa Nagarajan, V. H. Savitha, B. Subramaniyan   +2 more
doaj   +1 more source