Results 71 to 80 of about 329,448 (411)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Relationship between phonemic discrimination ability and articulation in cochlear implanted preschool children [PDF]

Specijalna Edukacija i Rehabilitacija
Introduction. The acquisition of the native language is achieved through mastering the phonological system, which relies on the development of phonemic discrimination and articulation. Objectives.
Bjelić Marija P., Isaković Ljubica S., Veletić Marija M., Kordić Milena B.   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Leveraging sponsorships on the Internet: Activation, congruence, and articulation [PDF]

, 2008
This paper considers how the Internet can be used to leverage commercial sponsorships to enhance audience attitudes toward the sponsor. Definitions are offered that distinguish the terms leverage and activation with respect to sponsorship-linked ...
Cornwell, T. Bettina, Drennan, Judy C., Clinton S. Weeks, T. Bettina Cornwell, Judy C. Drennan, Drennan, Judy, Weeks, Clinton S.   +6 more
core   +1 more source

Displacement and Articulation Rhetoric in Sa'adi's Golestān [PDF]

مطالعات زبانی و بلاغی
In every text, there are two levels of ambiguity of translation and ratio, which are the basis of the rhetorical explanation of the text from different perspectives of textual analysis, whether formalistic or discursive.
Omer Mohammad Saeed, Parsa Yaghoobi Janbeh saraei   +1 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Getting the Message: supporting students’ transition from Higher National to degree level study and the role of mobile technologies. [PDF]

, 2012
In this paper, we explore roles that mobile technologies can play in supporting students’ transition to second and third year of university degree study, specifically along articulation routes from completing a Higher National Certificate (HNC) or Higher
Fotheringham, Julia, Alder, Emily
core  

Adolescent fathers and mothers in the parenting exercise

Ciencia y Cuidado, 2017
Introduction: In general, parenting has been considered as the actions of socialization led by adults, which consider teenagers as unable people to achieve trajectories of the expected ideal development for girls and boys; on the other side the State ...
Doris Amparo Parada-Rico , Carlos Iván García-Suárez   +1 more
doaj  

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Functional Organization of Human Sensorimotor Cortex for Speech Articulation

Nature, 2013
Speaking is one of the most complex actions that we perform, but nearly all of us learn to do it effortlessly. Production of fluent speech requires the precise, coordinated movement of multiple articulators (for example, the lips, jaw, tongue and larynx)
Kristofer E. Bouchard, N. Mesgarani, Keith Johnson, E. Chang   +3 more
semanticscholar   +1 more source