Results 41 to 50 of about 65,394 (259)

A method to increase reproducibility in adult ventricular myocyte sizing and flow cytometry: Avoiding cell size bias in single cell preparations. [PDF]

open access: yes, 2017
RATIONALE:Flow cytometry (FCM) of ventricular myocytes (VMs) is an emerging technology in adult cardiac research that is challenged by the wide variety of VM shapes and sizes.
Aminololama-Shakeri, Shadi   +4 more
core   +3 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Sampling Matters: What Simulation Modeling and Microrefuse Sampling Practice Reveal about Archaeological Sampling, Training, and Design

open access: yesAdvances in Archaeological Practice
Archaeological sampling is a critical yet inconsistently applied aspect of field methodology. Poorly designed strategies produce biased or irreproducible results, especially when recovery is labor-intensive and research expectations are high.
Isaac Imran Taber Ullah
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky   +8 more
wiley   +1 more source

Nonlinear X-Wave Ultrasound Imaging of Acoustic Biomolecules

open access: yesPhysical Review X, 2018
The basic physics of sound waves enables ultrasound to visualize biological tissues with high spatial and temporal resolution. Recently, this capability was enhanced with the development of acoustic biomolecules—proteins with physical properties enabling
David Maresca   +4 more
doaj   +1 more source

Outer Regions of the Cluster Gaseous Atmospheres [PDF]

open access: yes, 1999
We present a systematic study of the hot gas distribution in the outer regions of regular clusters using ROSAT PSPC data. Outside the cooling flow region, the beta-model describes the observed surface brightness closely, but not precisely.
A. Vikhlinin   +13 more
core   +2 more sources

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim   +3 more
wiley   +1 more source

Archeological Investigations on the Weyerhaeuser Land Exchange Sites, McCurtain County, Oklahoma: An Update [PDF]

open access: yes, 2001
This paper provides a brief overview of the testing work completed to date on sites within the Tiak Ranger District. Ouachita National Forest. McCurtain County, Oklahoma.
Etchieson, Meeks
core   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang   +10 more
wiley   +1 more source

Scattering Elimination in 2D IR Immune from Detector Artifacts

open access: yesThe Journal of Physical Chemistry B
Highly scattering samples, such as polymer droplets or solid-state powders, are difficult to study via coherent two-dimensional infrared (2D IR) spectroscopy. Previously, researchers have employed (quasi-) phase cycling, local-oscillator chopping, and polarization control to reduce scattering, but the latter method poses a limit on polarization ...
Anneka Miller Casas   +4 more
openaire   +4 more sources

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