Results 51 to 60 of about 492,817 (314)
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Influence of High Pass Filter Settings on Motor Evoked Potentials
Frontiers in Neuroscience, 2021 ObjectiveMotor evoked potentials (MEP), obtained by transcranial magnetic stimulation (TMS) are a common tool in clinical research and diagnostic. Nevertheless, reports regarding the influence of filter settings on MEP are sparse.
Petyo Nikolov +7 more
doaj +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Brain Extraction From Brain MRI Images Based on Wasserstein GAN and O-Net
IEEE Access, 2021 Brain extraction is an essential pre-processing step for neuroimaging analysis. It is difficult to achieve high-precision extraction from low-quality brain MRI images with artifacts and gray inconsistencies which often result in irregular hole regions in
Shaofeng Jiang +5 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
SAREC-Lab/SAFA-Artifacts: SAFA Artifacts
, 2019 <p>In this repository we make a set of artifacts available that were used for experiments in the paper:</p> <p>Leveraging Artifact Trees to Evolve and Reuse Safety Cases Ankit Agrawal, Seyedehzahra Khoshmanesh, Michael Vierhauser, Mona ...
Ankit Agrawal +2 more
core +1 more source
BuildingsTo study the dynamic response of multi-span mortise and tenon stone bridges under natural excitation, a bluestone multi-span stone bridge with a main span of 2.56 m in southern China was taken as the research object.
Jiaxing Hu +3 more
doaj +1 more source
Mobile Forensics Analysis for Instant Messaging Applications Namely TamTam and Botim [PDF]
مجلة جامعة النجاح للأبحاث العلوم الطبيعيةCybercrimes are rapidly increasing in parallel with the usage of digital tools. Criminals can use many methods to carry out their crimes such as mobile phones and instant messaging applications. Because of that, it is important to investigate the ability
Alsharif H. Aburbeian +2 more
doaj +1 more source
Artifacts and Essentialism [PDF]
Review of Philosophy and Psychology, 2013 Psychological essentialism is an intuitive folk belief positing that certain categories have a non-obvious inner "essence" that gives rise to observable features. Although this belief most commonly characterizes natural kind categories, I argue that psychological essentialism can also be extended in important ways to artifact concepts.
openaire +2 more sources
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source