Results 61 to 70 of about 585,749 (296)

In Situ Testing and Finite Element Analysis of a Discontinuous Mortise and Tenon Stone Bridge Under Natural Excitation

open access: yesBuildings
To study the dynamic response of multi-span mortise and tenon stone bridges under natural excitation, a bluestone multi-span stone bridge with a main span of 2.56 m in southern China was taken as the research object.
Jiaxing Hu   +3 more
doaj   +1 more source

Brain Extraction From Brain MRI Images Based on Wasserstein GAN and O-Net

open access: yesIEEE Access, 2021
Brain extraction is an essential pre-processing step for neuroimaging analysis. It is difficult to achieve high-precision extraction from low-quality brain MRI images with artifacts and gray inconsistencies which often result in irregular hole regions in
Shaofeng Jiang   +5 more
doaj   +1 more source

The IT Artifact and Telecommuting [PDF]

open access: yes, 2007
Research on the concept of telecommuting or telework, as it is known in various areas of the world, has appeared in information systems (IS) and non-IS publications for more than 20 years. Research areas with respect to telecommuting are quite varied, from Information and Communication Technologies (ICT) use, to transportation, managerial control, work-
France Bélanger   +4 more
openaire   +1 more source

Defects and failures in legal artifacts

open access: yes, 2022
[Extract]Much progress has been made in recent years in understanding the role of functions in defining legal artifacts. Authors such as Luka Burazin, Ken Ehrenberg, Mark Murphy, Corrado Roversi, and myself have advanced substantive theories of the ...
Crowe, Jonathan
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Bone artifacts from Riwi Cave, south‐central Kimberley: Reappraisal of the timing and role of osseous artifacts in northern Australia

open access: yes, 2021
Here, we describe eight bone artifacts recovered from Pleistocene and Holocene contexts at Riwi, a cave site located in Mimbi country of the south-central Kimberley.
Langley, Michelle C   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

uc-cdis/pfb-paper-artifacts: DOI publishing for paper

open access: yes, 2022
Artifacts of PFB and json information for PFB ...
cmlsn   +2 more
core   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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