Results 61 to 70 of about 5,372,669 (352)

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Examples of Artificial Perceptions in Optical Character Recognition and Iris Recognition

, 2012
This paper assumes the hypothesis that human learning is perception based, and consequently, the learning process and perceptions should not be represented and investigated independently or modeled in different simulation spaces.
A.M. Turing, D. Bhattacharjee, L.A. Zadeh, M. Sugeno, T. Kohonen, V.E. Balas, W. McCullock   +6 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Challenges and prospects for consumer acceptance of cultured meat

Journal of Integrative Agriculture, 2015
Consumer acceptance of cultured meat is expected to depend on a wide diversity of determinants ranging from technology-related perceptions to product-specific expectations, and including wider contextual factors like media coverage, public involvement ...
Wim Verbeke, Pierre Sans, Ellen J Van Loo   +2 more
doaj   +1 more source

Road map for research on responsible artificial intelligence for development (AI4D) in African countries: The case study of agriculture [PDF]

, 2021
Arthur Gwagwa, Emre Kazim, Patti Kachidza, Airlie Hilliard, Kathleen Siminyu, Matthew L. Smith, John Shawe‐Taylor   +6 more
openalex   +1 more source

Artificial neural networks [PDF]

, 2017
Nowadays we are living in the age of computers, and we are systematically making our way to creating artificial intelligence. In addition, one of possible directions to make AI come true is to find the way of generalizing ...
Korotenko, L.M., Nechai, N.M., Teslenko, Svyatoslav   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Artificial limb connection [PDF]

, 1974
Connection simplifies and eases donning and removing artificial limb; eliminates harnesses and clamps; and reduces skin pressures by allowing bone to carry all tensile and part of compressive loads between prosthesis and stump.
Owens, L. J.
core   +1 more source

Artificial Sequences and Complexity Measures [PDF]

, 2005
In this paper we exploit concepts of information theory to address the fundamental problem of identifying and defining the most suitable tools to extract, in a automatic and agnostic way, information from a generic string of characters.
, , , , , Andrea Baronchelli, Baronchelli A Caglioti E Loreto V Puglisi A, Bell T C, Cai H Kulkarni S Verdú S, Cavalli-Sforza L L, Chaitin G J, Chaitin G J, Cilibrasi R, El-Yaniv R, Emanuele Caglioti, Falcioni M Palatella L Pigolotti S Vulpiani A, Farach M Noordewier M Savari S Shepp L Wyner A Ziv J, Farris J S, Felsenstein J, Grassberger P, Juola P, Kaltchenko A, Khinchin A I, Kolmogorov A N, Kukushkina O V, Kullback S, Li M, Loewenstern D Hirsh H Yianilos P Noordewieret M, Londei A, Loreto V, Menconi G, Nevill-Manning C, Pierce J R, Renfrew C, Saitou N, Shannon C E, Shannon C E, Sinai Y G, Teahan W J, Thaper N, Vittorio Loreto, Welsh D, Wyner A D, Zurek W H   +43 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source