Results 71 to 80 of about 5,372,669 (352)

The Artificial Intelligence Course at the Faculty of Computer Science in the Polytechnic University of Madrid [PDF]

open access: yes, 1994
This paper presents the experience of teaching an Artificial Intelligence course at the Faculty of Computer Science in the Polytechnic University of Madrid, Spain.
Gómez-Pérez, A., Juristo, N.
core   +1 more source

Observation of Light Guiding by Artificial Gauge Fields

open access: yes, 2018
The use of artificial gauge fields enables systems of uncharged particles to behave as if affected by external fields. Generated by geometry or external modulation, artificial gauge fields have been instrumental in demonstrating topological phenomena in ...
Bandres, Miguel A.   +6 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Limits of Information Science: Limits of Aims, Processes and Results

open access: yesArtefactos, 2020
The problem of information science can be analyzed following several steps. First, there is the issue of the angle of analysis, which can be oriented in two directions: a) to consider information science from the viewpoint of its boundaries as scientific
Antonio BEREIJO
doaj   +1 more source

XAI-Explainable artificial intelligence [PDF]

open access: yes, 2019
Explainability is essential for users to effectively understand, trust, and manage powerful artificial intelligence ...
Choi, J.   +5 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

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