Results 91 to 100 of about 9,399 (221)

Cardiovascular Autonomic Neuropathy in Charcot–Marie–Tooth Disease: A Genotype‐Stratified Study of PMP22 Duplication and GJB1 Mutation Carriers

open access: yesJournal of the Peripheral Nervous System, Volume 31, Issue 4, December 2026.
ABSTRACT Background and Aims Data on cardiovascular autonomic neuropathy (CAN) are sparse in Charcot–Marie–Tooth disease. We aimed to determine the prevalence of CAN in CMT1A and CMTX1 and its associations with neuropathy severity and heart rate variability (HRV), compared with age‐ and sex‐matched controls. Methods Thirty‐six CMT1A, 24 CMTX1 patients,
Kryštof Prášil   +4 more
wiley   +1 more source

Evaluation of a novel fetal echocardiography training programme in two tertiary care obstetric Centres

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 771-778, November 2026.
Abstract Objectives Improving and maintaining high detection rates for major congenital heart disease (CHD) is a priority for successful prenatal anatomy screening programmes. The primary objective of this study was to evaluate the utility of on‐site multidimensional targeted training in fetal cardiac screening. Methods A prospective study evaluating a
Fiona Cody   +6 more
wiley   +1 more source

Late INa as a Therapeutic Target: New Strategies, Computational Modelling, Drug Development, and Clinical Translation

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1939-1957, November 2026.
ABSTRACT The Nav1.5 channel, a major isoform of voltage‐gated sodium ion channel, is mainly found in ventricular cardiomyocytes, playing a key role in generating essential cardiac action potentials for normal heart rhythms. Mutations in Nav1.5 have been associated with severe heart conditions such as long QT syndrome, Brugada syndrome, cardiac ...
Arkapravo Chattopadhyay   +3 more
wiley   +1 more source

Multitarget Drug Design for Cardiovascular Disease: Bridging Chemistry and Medicine

open access: yesChemMedChem, Volume 21, Issue 19, 14 October 2026.
Many pathophysiological pathways associated with cardiovascular diseases involve multiple drug targets. This article reviews recent advances in the development of pharmacological compounds capable of simultaneously modulating multiple mechanisms. Multitarget drugs offer a promising therapeutic approach for complex cardiovascular disorders, including ...
Gyuzel Y. Mitronova   +3 more
wiley   +1 more source

Soft Skins With Reversible Thickness Morphing: Materials, Mechanisms, and Applications

open access: yesAdvanced Materials, Volume 38, Issue 55, 1 October 2026.
Evolution of electronic skin (e‐skin) technologies toward adaptive, multifunctional soft skins. Phase I highlights early rigid and discrete sensory interfaces. Phase II shows the transition toward flexible, stretchable, and large‐area e‐skin. Phase III captures the emergence of computational e‐skin.
Oliver Ozioko   +2 more
wiley   +1 more source

Potential and Trend of MXene in Smart Biocomposites Applications: A Review

open access: yesAdvanced Sustainable Systems, Volume 10, Issue 10, October 2026.
MXene‐based biocomposites emerge as a promising class of multifunctional materials that integrate the exceptional electrical, thermal, and electrochemical properties of MXenes with the biocompatibility and sustainability of biopolymers. This review examines their synthesis, fabrication, and structure–property relationships while highlighting ...
Joy Chigozie Anene‐Amaechi   +3 more
wiley   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, Volume 13, Issue 57, 14 October 2026.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source

Natural history of artificial urinary sphincter cuff erosion in males: Experience from two tertiary centres in the United Kingdom

open access: yesBJUI Compass, Volume 7, Issue 10, October 2026.
Abstract Objectives This study aimed to describe the natural history of urethral cuff erosion (UCE) following artificial urinary sphincter (AUS) implantation, including the incidence of urethral stricture and fistula formation, and the outcomes of salvage AUS reimplantation, based on the experience of two UK tertiary centres.
Loufopoulos Ioannis   +13 more
wiley   +1 more source

Validation of an Automated Artificial Intelligence‐Driven Planner for Transcatheter Aortic Valve Replacement

open access: yesCatheterization and Cardiovascular Interventions, Volume 108, Issue 4, Page 1473-1481, October 1, 2026.
ABSTRACT Background Preprocedural planning with multislice computed tomography (MSCT) is an essential prerequisite for successful transcatheter aortic valve replacement (TAVR). However, preprocedural planning is time‐consuming and may contain clinically meaningful interobserver variability.
Mark M. P. van den Dorpel   +11 more
wiley   +1 more source

P4856Prospective study of thromboembolic events after reoperation in permanent artificial cardiac pacing [PDF]

open access: yesEuropean Heart Journal, 2018
C M Albertini   +4 more
openaire   +1 more source

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