Results 161 to 170 of about 3,013,083 (257)

Mass Spectrometry Imaging–Guided Proteomics, an Emerging Frontier in Spatial Biology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Spatial heterogeneity is a defining feature of tissue organization, yet conventional proteomic analysis provides limited information about the spatial origins of identified proteins. Spatially guided proteomics addresses this limitation by using tissue imaging techniques to select regions of interest (ROIs) for localized analysis by liquid ...
Kenneth Weke, Julian J. Lum, David R. Goodlett, Helena Pětrošová, Irena Dapic   +4 more
wiley   +1 more source

Artificial Intelligence for Outcome Prediction in Patients with Hypoxic-Ischemic Encephalopathy after Cardiac Arrest

ARTIFICIAL INTELLIGENCE FOR OUTCOME PREDICTION IN PATIENTS WITH HYPOXIC-ISCHEMIC ENCEPHALOPATHY AFTER CARDIAC ARREST Artificial Intelligence for Outcome Prediction in Patients with Hypoxic-Ischemic Encephalopathy after Cardiac Arrest / Molinski, Noah ...
Molinski, Noah Salomon
core  

Recent Developments, Applications, and Future Prospects of Advanced Hearts-on-a-Chip. [PDF]

Micromachines (Basel)
Kang A, Lee H, Park G, Kim T, Kim H, Park T, Staley S, Kang M, Kang YA.   +8 more
europepmc   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

Med Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang, Huihui Yang, Guangxin Li, Guobang Liu, Zhulan Chen, Wenzhi Tian, Meiyang Huang, Xiaoling Liu, Yongsheng Zhao, Dong Chen   +9 more
wiley   +1 more source

SHP2 in Cancer: From Tumor Biology to Therapeutic Targeting

Medicinal Research Reviews, EarlyView.
ABSTRACT SHP2 is a tyrosine phosphatase that mediates intracellular signaling downstream of transmembrane receptors regulated by a pair of src homology 2 (SH2) domains. Its overexpression and mutation are pivotal in driving tumor progression by influencing various cancer's fundamental characteristics, such as metastasis, DNA repair, angiogenesis ...
Maryam Jama, Michael Overduin, Khaled H. Barakat   +2 more
wiley   +1 more source

Accelerated MR Elastography Using Learned Neural Network Representation

Magnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To develop a deep‐learning method for achieving fast high‐resolution MR elastography from highly undersampled data without the need for high‐quality training datasets. Methods We first reframed the deep neural network representation as a nonlinear extension of the linear subspace model, then used it to represent and reconstruct MRE ...
Xi Peng
wiley   +1 more source

Dopaminergic neurons linking threat processing to cardiac modulation and locomotor responses. [PDF]

Elife
Tsuji M, Jinkoma D, Uemura Y, Ogasawara A, Emoto K.   +4 more
europepmc   +1 more source

Enhanced Recovery After Surgery in Simultaneous Pancreas–Kidney Transplantation: A Retrospective Cohort Analysis of Perioperative Outcomes

Organ Medicine, EarlyView.
ABSTRACT Background While simultaneous pancreas–kidney transplantation (SPK) is an established therapeutic intervention for patients with end‐stage renal disease and diabetes, it has been associated with prolonged recovery periods and high complication rates.
Rongxin Chen, Luhao Liu, Jialin Wu, Zhuangqiang Fang, Guanghui Li, Zheng Chen   +5 more
wiley   +1 more source

Electrical stimulation of cardiac adipose tissue-derived progenitor cells modulates cell phenotype and genetic machinery

A major challenge of cardiac tissue engineering is directing cells to establish the physiological structure and function of the myocardium being replaced.
Rosell Ferrer, Francisco Javier, Gálvez Montón, Carolina, Bayés Genis, Antoni, Roura, Santiago, Prat Vidal, Cristina, Sanchez, B., Soler Botija, Carolina, Llucia Valldeperes, A., Bragós Bardia, Ramon   +8 more
core  

MMP12 induces fibrogenic macrophage differentiation to drive granuloma-associated cardiac fibrosis. [PDF]

Am J Respir Crit Care Med
Mazić M, Lim CX, Saha P, El-Jammal T, Šango R, Ghazi T, Jahić A, Ettel P, Jager J, Asimaki A, Sheppard MN, Todt H, Kratky D, Hengstschläger M, Yang W, Weichhart T.   +15 more
europepmc   +1 more source