Results 21 to 30 of about 7,311,828 (299)

Roadmap to Building a Cell: An Evolutionary Approach

Frontiers in Bioengineering and Biotechnology, 2020
Laboratory synthesis of an elementary biological cell from isolated components may aid in understanding of the fundamental principles of life and will provide a platform for a range of bioengineering and medical applications.
Zhanar Abil, Christophe Danelon
doaj   +1 more source

Reproducible reformation of a bilayer lipid membrane using microair bubbles

Droplet, 2023
Planar bilayer lipid membranes (BLMs) are widely used as models for cell membranes in various applications, including drug discovery and biosensors. However, the nanometer‐thick bilayer structure, assembled through hydrophobic interactions of amphiphilic
Izumi Hashimoto, Toshihisa Osaki, Hirotaka Sugiura, Hisatoshi Mimura, Sho Takamori, Norihisa Miki, Shoji Takeuchi   +6 more
doaj   +1 more source

Immunogenicity, Efficacy, and Safety of a Novel Synthetic Microparticle Pre-Erythrocytic Malaria Vaccine in Multiple Host Species

Vaccines, 2023
We previously reported a protective antibody response in mice immunized with synthetic microparticle vaccines made using layer-by-layer fabrication (LbL-MP) and containing the conserved T1BT* epitopes from the P. falciparum circumsporozoite protein.
Thomas J. Powell, Jie Tang, Robert Mitchell, Mary E. DeRome, Andrea Jacobs, Naveen Palath, Edwin Cardenas, Michelle Yorke, James G. Boyd, Stephen A. Kaba, Elizabeth Nardin   +10 more
doaj   +1 more source

Microparticle RSV Vaccines Presenting the G Protein CX3C Chemokine Motif in the Context of TLR Signaling Induce Protective Th1 Immune Responses and Prevent Pulmonary Eosinophilia Post-Challenge

Vaccines, 2022
Layer-by-layer microparticle (LbL-MP) fabrication was used to produce synthetic vaccines presenting a fusion peptide containing RSV G protein CX3C chemokine motif and a CD8 epitope of the RSV matrix protein 2 (GM2) with or without a covalently linked ...
Thomas J. Powell, Andrea Jacobs, Jie Tang, Edwin Cardenas, Naveen Palath, Jennifer Daniels, James G. Boyd, Harrison C. Bergeron, Patricia A. Jorquera, Ralph A. Tripp   +9 more
doaj   +1 more source

Artificial cell microcapsules containing live bacterial cells and activated charcoal for managing renal failure creatinine: preparation and in-vitro analysis

The EuroBiotech Journal, 2019
Activated charcoal was microencapsulated with Lactobacillus acidophilus 314 previously adapted for urea uptake. The creatinine removal capacity of this combination microcapsule was evaluated in-vitro in media simulating the small intestine.
Lim Trisna, Ouyang Wei, Martoni Christopher John, Balit Nasri, Prakash Satya   +4 more
doaj   +1 more source

Artificial Intelligence for Image Analysis in Oral Squamous Cell Carcinoma: A Review [PDF]

, 2023
Head and neck tumor differential diagnosis and prognosis have always been a challenge for oral pathologists due to their similarities and complexity.
Deepak Pandiar, Vanesa Pereira-Prado, Mario Isiordia-Espinoza, Bologna-Molina, Ronell, Felipe Martins-Silveira, Sicco, Estefanía, González González, Rogelio, Rogelio González, Pandiar, Deepak, Jimena Hochmann, Isiordia-Espinoza, Mario Alberto, Estafanía Sicco, Ronell Bologna-Molina, Pereira-Prado, Vanesa, Silveira, Felipe Martins, Hochmann Valls, Jimena   +15 more
core   +1 more source

ARTIFICIAL CELL evolves into nanomedicine, biotherapeutics, blood substitutes, drug delivery, enzyme/gene therapy, cancer therapy, cell/stem cell therapy, nanoparticles, liposomes, bioencapsulation, replicating synthetic cells, cell encapsulation/scaffold, biosorbent/immunosorbent haemoperfusion/plasmapheresis, regenerative medicine, encapsulated microbe, nanobiotechnology, nanotechnology

Artificial Cells, Nanomedicine, and Biotechnology, 2019
It is only in the last 20 years that many of the original ideas on artificial cells are being increasingly applied and extended by researchers around the world.
Thomas Ming Swi Chang
doaj   +1 more source

An annotated high-content fluorescence microscopy dataset with Hoechst 33342-stained nuclei and manually labelled outlines

Data in Brief, 2023
Automated detection of cell nuclei in fluorescence microscopy images is a key task in bioimage analysis. It is essential for most types of microscopy-based high-throughput drug and genomic screening and is often required in smaller scale experiments as ...
Malou Arvidsson, Salma Kazemi Rashed, Sonja Aits   +2 more
doaj   +1 more source

The evolution of robust development and homeostasis in artificial organisms [PDF]

, 2008
During embryogenesis, multicellular animals are shaped via cell proliferation, cell rearrangement, and apoptosis. At the end of development, tissue architecture is then maintained through balanced rates of cell proliferation and loss. Here, we take an in
Baum, B, Basanta, D, Miodownik, M, David Basanta, Mark Miodownik, Buzz Baum   +5 more
core   +1 more source

Meta-analysis of contrast-enhanced ultrasound and contrast-enhanced harmonic endoscopic ultrasound for the diagnosis of gallbladder malignancy

BMC Medical Informatics and Decision Making, 2020
Background The diagnosis between benign and malignant gallbladder lesions is sometimes difficult. The objective of this study is to assess whether contrast-enhanced ultrasound (CEUS) and contrast-enhanced harmonic endoscopic ultrasound (CH-EUS) can be an
Xue Liang, Xiang Jing
doaj   +1 more source