Results 51 to 60 of about 409,880 (275)
Frontiers in Medicine, 2021 Background: The tumour immune microenvironment plays an important role in the biological mechanisms of tumorigenesis and progression. Artificial intelligence medicine studies based on big data and advanced algorithms are helpful for improving the ...
Tingshan He +4 more
doaj +1 more source
Molecular cancer prevention: Intercepting disease
Molecular Oncology, EarlyView.Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco +2 more
wiley +1 more source
Application of Artificial Immune System Approach in MRI Classification
EURASIP Journal on Advances in Signal Processing, 2008 Numerous scholars have submitted the theory and research of artificial immune systems (AISs) in recent years. Although AIS has been used in various fields, applying the AIS to medical images is very rare.
Gia-Hao Chang +3 more
doaj +1 more source
Artificial immune system agent model [PDF]
, 2011 The Artificial Immune Systems (AIS) is a biologically inspired techniques that emulates a natural system, in particular the vertebrate immune system, in order to develop computational tools for solving engineering problems.Immunity-based technique emerge
Che Doi, Siti Mazura, Md Norwawi, Norita
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Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
IEEE Access, 2021 With the increasing pressure from the market and the surge of “Industry 4.0,” staying competitive and relevant is becoming more and more difficult.
Mohd Nor Akmal Khalid, Umi Kalsom Yusof
doaj +1 more source
Representation in the (Artificial) Immune System [PDF]
Journal of Mathematical Modelling and Algorithms, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
McEwan, Chris, Hart, Emma
openaire +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
An Artificial Immune System Based Recommender [PDF]
, 2002 The immune system is a complex biological system with a highly distributed, adaptive and self-organising nature. This paper presents an artificial immune system (AIS) that exploits some of these characteristics and is applied to the task of film ...
Aickelin, Uwe, Cayzer, Steve
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