Results 1 to 10 of about 101,985 (265)

Development and Validation of a 28-gene Hypoxia-related Prognostic Signature for Localized Prostate Cancer

EBioMedicine, 2018
Background: Hypoxia is associated with a poor prognosis in prostate cancer. This work aimed to derive and validate a hypoxia-related mRNA signature for localized prostate cancer.
Darragh Mcart, Syed Haider, Darren Roberts   +2 more
exaly   +3 more sources

Identification of a Novel Glycosyltransferase Prognostic Signature in Hepatocellular Carcinoma Based on LASSO Algorithm

Frontiers in Genetics, 2022
Although many prognostic models have been developed to help determine personalized prognoses and treatments, the predictive efficiency of these prognostic models in hepatocellular carcinoma (HCC), which is a highly heterogeneous malignancy, is less than ...
Zhiyang Zhou, Tao Wang, Yao Du, Junping Deng, Ge Gao, Jiangnan Zhang   +5 more
doaj   +1 more source

Identification of a Costimulatory Molecule-Related Signature for Predicting Prognostic Risk in Prostate Cancer

Frontiers in Genetics, 2021
Costimulatory molecules have been proven to enhance antitumor immune responses, but their roles in prostate cancer (PCa) remain unexplored. In this study, we aimed to explore the gene expression profiles of costimulatory molecule genes in PCa and ...
Shengdong Ge, Shengdong Ge, Shengdong Ge, Xiaoliang Hua, Xiaoliang Hua, Xiaoliang Hua, Juan Chen, Haibing Xiao, Haibing Xiao, Haibing Xiao, Li Zhang, Li Zhang, Li Zhang, Jun Zhou, Jun Zhou, Jun Zhou, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang, Sheng Tai, Sheng Tai, Sheng Tai   +21 more
doaj   +1 more source

Identification of a novel signature based on unfolded protein response-related gene for predicting prognosis in bladder cancer

Human Genomics, 2021
Highlights 1. We first comprehensive investigated the expression, protein–protein interaction, and prognostic value of unfolded protein response-related gene in bladder cancer. 2.
Ke Zhu, Liu Xiaoqiang, Wen Deng, Gongxian Wang, Bin Fu   +4 more
doaj   +1 more source

Integrative Analysis Constructs an Extracellular Matrix-Associated Gene Signature for the Prediction of Survival and Tumor Immunity in Lung Adenocarcinoma

Frontiers in Cell and Developmental Biology, 2022
Background: Lung adenocarcinoma (LUAD) accounts for the majority of lung cancers, and the survival of patients with advanced LUAD is poor. The extracellular matrix (ECM) is a fundamental component of the tumor microenvironment (TME) that determines the ...
Lingyan Xiao, Qian Li, Yongbiao Huang, Zhijie Fan, Wan Qin, Bo Liu, Xianglin Yuan   +6 more
doaj   +1 more source

Construction and Validation of Novel Diagnostic and Prognostic DNA Methylation Signatures for Hepatocellular Carcinoma

Frontiers in Genetics, 2020
Hepatocellular carcinoma (HCC) is one of the most prevalent life-threatening human cancers and the leading cause of cancer-related mortality, with increased global incidence within the last decade.
Ran Li, Liyan Shui, Junling Jia, Junling Jia, Chao Wu   +4 more
doaj   +1 more source

A novel pyroptosis-related prognostic signature for lung adenocarcinoma: Identification and multi-angle verification

Frontiers in Genetics, 2023
Background: Lung adenocarcinoma (LUAD) is an aggressive disease of heterogeneous characteristics with poor prognosis and high mortality. Pyroptosis, a newly uncovered type of programmed cell death with an inflammatory nature, has been determined to hold ...
Xinyue Wang, Xinyue Wang, Xinyue Wang, Jing Zhou, Jing Zhou, Jing Zhou, Zhaona Li, Zhaona Li, Zhaona Li, Xiuqiong Chen, Xiuqiong Chen, Xiuqiong Chen, Qianhui Wei, Qianhui Wei, Qianhui Wei, Kaidi Chen, Kaidi Chen, Kaidi Chen, Richeng Jiang, Richeng Jiang, Richeng Jiang   +20 more
doaj   +1 more source

A seven-gene prognostic signature predicts overall survival of patients with lung adenocarcinoma (LUAD)

Cancer Cell International, 2021
Background Lung adenocarcinoma (LUAD) is one of the most common types in the world with a high mortality rate. Despite advances in treatment strategies, the overall survival (OS) remains short.
Aisha Al-Dherasi, Qi-Tian Huang, Yuwei Liao, Sultan Al-Mosaib, Rulin Hua, Yichen Wang, Ying Yu, Yu Zhang, Xuehong Zhang, Chao Huang, Haithm Mousa, Dongcen Ge, Sufiyan Sufiyan, Wanting Bai, Ruimei Liu, Yanyan Shao, Yulong Li, Jingkai Zhang, Leming Shi, Dekang Lv, Zhiguang Li, Quentin Liu   +21 more
doaj   +1 more source

Development of a novel glycolysis-related genes signature for isocitrate dehydrogenase 1-associated glioblastoma multiforme

Frontiers in Immunology, 2022
BackgroundThe significant difference in prognosis between IDH1 wild-type and IDH1 mutant glioblastoma multiforme (GBM) may be attributed to their metabolic discrepancies. Hence, we try to construct a prognostic signature based on glycolysis-related genes
Xiaomin Cai, Zheng Chen, Caiquan Huang, Jie Shen, Wenxian Zeng, Shuang Feng, Yu Liu, Shiting Li, Ming Chen   +8 more
doaj   +1 more source

A Novel Gene Prognostic Signature Based on Differential DNA Methylation in Breast Cancer

Frontiers in Genetics, 2021
Background: DNA methylation played essential roles in regulating gene expression. The impact of DNA methylation status on the occurrence and development of cancers has been well demonstrated.
Chunmei Zhu, Shuyuan Zhang, Di Liu, Qingqing Wang, Qingqing Wang, Ningning Yang, Ningning Yang, Zhewen Zheng, Zhewen Zheng, Qiuji Wu, Qiuji Wu, Qiuji Wu, Yunfeng Zhou, Yunfeng Zhou, Yunfeng Zhou   +14 more
doaj   +1 more source