Results 21 to 30 of about 812,903 (257)

Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer

Frontiers in Oncology, 2022
BackgroundEnergy metabolism has been considered as one of the novel features of neoplasms. This study aimed to establish the prognostic signature for pancreatic cancer (PC) based on metabolism-related genes (MRGs).MethodsWe obtained MRGs from the ...
Hui Chen, Fuqiang Zu, Taofei Zeng, Ziang Chen, Jinhong Wei, Peng Liu, Zeyu Li, Lei Zhou, Huaitao Wang, Hao Tan, Xiaodong Tan   +10 more
doaj   +1 more source

Exploration of prognostic genes and risk signature in breast cancer patients based on RNA binding proteins associated with ferroptosis

Frontiers in Genetics, 2023
Background: Breast cancer (BRCA) is a life-threatening malignancy in women with an unsatisfactory prognosis. The purpose of this study was to explore the prognostic biomarkers and a risk signature based on ferroptosis-related RNA-binding proteins (FR ...
Xiang Chen, Changcheng Yang, Wei Wang, Xionghui He, Hening Sun, Wenzhi Lyu, Kejian Zou, Shuo Fang, Shuo Fang, Zhijun Dai, Huaying Dong   +10 more
doaj   +1 more source

Epigenetics in diagnosis, prognostic assessment and treatment of cancer:An update [PDF]

, 2014
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and ...
Crook, Tim, Briasoulis, Evangelos, Sim, Van Ren, Hatzimichael, Eleftheria, Lagos, Konstantinos   +4 more
core   +1 more source

Image1_Construction and Validation of a 15-Top-prognostic-gene-based Signature to Indicate the Dichotomized Clinical Outcome and Response to Targeted Therapy for Bladder Cancer Patients.PDF

, 2022
The clinical outcome of heterogeneous bladder cancer (BCa) is impacted by varying molecular characteristics and clinical features, and new molecular classification is necessary to recognize patients with dichotomized prognosis. We enrolled a total of 568
Chaozhao Liang (212565), Hongbing Gu (12220847)   +1 more
core   +1 more source

An energy metabolism-based eight-gene signature correlates with the clinical outcome of esophagus carcinoma

BMC Cancer, 2021
Background The essence of energy metabolism has spread to the field of esophageal cancer (ESC) cells. Herein, we tried to develop a prognostic prediction model for patients with ESC based on the expression profiles of energy metabolism associated genes ...
Weifeng Zheng, Chaoying Chen, Jianghao Yu, Chengfeng Jin, Tiemei Han   +4 more
doaj   +1 more source

Construction of a prognostic signature for serous ovarian cancer based on lactate metabolism-related genes

Frontiers in Oncology, 2022
BackgroundThe key biochemical feature of malignant tumor is the conversion of energy metabolism from oxidative phosphorylation to glycolysis, which provides sufficient capacity and raw materials for tumor cell rapid growth.
Jiangdong Xiang, Rongjia Su, Sufang Wu, Lina Zhou   +3 more
doaj   +1 more source

Tumor-stroma derived gene expression patterns as prognosticators in breast cancer [PDF]

, 2010
The stroma, which embeds epithelial cells, plays a major role in the shaping and physiological regulation of animal organs such as the breast. Aberrant functioning of the stroma was found to support tumorigenesis and cancer progression.
Rajski, Michal
core   +1 more source

Construction of a prognostic signature of autophagy-related lncRNAs in non-small-cell lung cancer

BMC Cancer, 2021
Background Autophagy inhibits tumorigenesis by limiting inflammation. LncRNAs regulate gene expression at various levels as RNAs; thus, both autophagy and lncRNAs are closely related to the occurrence and development of tumours.
Xinyang Zhang, Yu Cao, Li Chen
doaj   +1 more source

Comprehensive analysis reveals a metabolic ten-gene signature in hepatocellular carcinoma [PDF]

PeerJ, 2020
Background Due to the complicated molecular and cellular heterogeneity in hepatocellular carcinoma (HCC), the morbidity and mortality still remains high level in the world.
Zhipeng Zhu, Lulu Li, Jiuhua Xu, Weipeng Ye, Borong Chen, Junjie Zeng, Zhengjie Huang   +6 more
doaj   +2 more sources

A robust six-gene prognostic signature for prediction of both disease-free and overall survival in non-small cell lung cancer

Journal of Translational Medicine, 2019
Background The high mortality of patients with non-small cell lung cancer (NSCLC) emphasizes the necessity of identifying a robust and reliable prognostic signature for NSCLC patients.
Shuguang Zuo, Min Wei, Hailin Zhang, Anxian Chen, Junhua Wu, Jiwu Wei, Jie Dong   +6 more
doaj   +1 more source