Results 11 to 20 of about 812,903 (257)

A prognostic gene expression signature for oropharyngeal squamous cell carcinoma [PDF]

EBioMedicine, 2020
Background: Robust prognostic stratification of patients with oropharyngeal squamous cell carcinoma (OPSCC) is important for developing individualized treatment plans.
Xinyi Liu, Ping Liu, Rebecca D. Chernock, Krystle A.Lang Kuhs, James S. Lewis, Jr., Jingqin Luo, Hiram A. Gay, Wade L. Thorstad, Xiaowei Wang   +8 more
doaj   +2 more sources

Hypoxia-immune-related microenvironment prognostic signature for osteosarcoma

Frontiers in Cell and Developmental Biology, 2022
Introduction: Increasing evidences have shown that hypoxia and the immune microenvironment play vital roles in the development of osteosarcoma. However, reliable gene signatures based on the combination of hypoxia and the immune status for prognostic ...
Wenshuo Zhang, Pang Lyu, Darja Andreev, Yewei Jia, Fulin Zhang, Aline Bozec   +5 more
doaj   +2 more sources

A Hybrid Prognostic Methodology and its Application to Well-Controlled Engineering Systems [PDF]

, 2015
This thesis presents a novel hybrid prognostic methodology, integrating physics-based and data-driven prognostic models, to enhance the prognostic accuracy, robustness, and applicability.
Eker, Ömer Faruk
core   +7 more sources

Prognostic gene expression signature for high-grade serous ovarian cancer [PDF]

, 2020
Background: Median overall survival (OS) for women with high-grade serous ovarian cancer (HGSOC) is ∼4 years, yet survival varies widely between patients. There are no well-established, gene expression signatures associated with prognosis.
Millstein, J., Elatre, W, Volchek, M, Gilks, B., Brown, B., Nazeran, T., Volchek, M., Chen, S, Anglesio, MS, Millstein, J, Hung, J, Links, M., Anglesio, M. S., Goode, E. L., Nazeran, T, Intermaggio, MP, Leong, HS, Elatre, W., Budden, T, Talhouk, A, Bentley, RC, Hill, J., Chen, S., Intermaggio, M. P., Talhouk, A., Gilks, B, Goode, EL, Leong, H. S., Budden, T., et al.   +29 more
core   +1 more source

Genome instability-derived genes as a novel prognostic signature for lung adenocarcinoma

Frontiers in Cell and Developmental Biology, 2023
Background: An increasing number of patients are being diagnosed with lung adenocarcinoma, but there remains limited progress in enhancing prognostic outcomes and improving survival rates for these patients.
Xu Zhang, Tak-Wah Lam, Hing-Fung Ting
doaj   +1 more source

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures [PDF]

, 2011
Background: Current prognostic gene signatures for breast cancer mainly reflect proliferation status and have limited value in triple-negative (TNBC) cancers.
Pusztai, Lajos, Lajos Pusztai, Schmidt Marcus, Karn, Thomas, Lars Hanker, Holtrich Uwe, Ruckhäberle Eugen, Volkmar Müller, Liedtke, Cornelia, Karn Thomas, Shiang Christine Y., Rody Achim, Gätje, Regine, Solbach Christine, Eugen Ruckhäberle, Pusztai Lajos, Müller, Volkmar, Cornelia Liedtke, Rody, Achim, Ahr Andre, Ruckhäberle, Eugen, Marcus Schmidt, Christine Y Shiang, Solbach, Christine, Gaetje Regine, Ahr, André, Andre Ahr, Thomas Karn, Hanker Lars, Achim Rody, Schmidt, Marcus, Shiang, Christine Y., Hanker, Lars, Takayuki Iwamoto, Holtrich, Uwe, Iwamoto Takayuki, Manfred Kaufmann, Liedtke Cornelia, Uwe Holtrich, Christine Solbach, Müller Volkmar, Iwamoto, Takayuki, Kaufmann Manfred, Kaufmann, Manfred, Regine Gaetje   +44 more
core   +1 more source

Intra-tumour signalling entropy determines clinical outcome in breast and lung cancer. [PDF]

, 2015
The cancer stem cell hypothesis, that a small population of tumour cells are responsible for tumorigenesis and cancer progression, is becoming widely accepted and recent evidence has suggested a prognostic and predictive role for such cells. Intra-tumour
Banerji, CR, Andrew E. Teschendorff (184707), Andrew E Teschendorff, Christopher R S Banerji, Carlos Caldas (1042), Carlos Caldas, Caldas, C, Simone Severini, Teschendorff, AE, Christopher R. S. Banerji (707702), Simone Severini (5662612), Severini, S   +11 more
core   +1 more source

Identification of Potential Prognostic Long Non-Coding RNA Biomarkers for Predicting Survival in Patients with Hepatocellular Carcinoma

Cellular Physiology and Biochemistry, 2018
Background/Aims: The aim of the current study was to identify potential prognostic long non-coding RNA (lncRNA) biomarkers for predicting survival in patients with hepatocellular carcinoma (HCC) using The Cancer Genome Atlas (TCGA) dataset and ...
Xiwen Liao, Chengkun Yang, Rui Huang, Chuangye Han, Tingdong Yu, Ketuan Huang, Xiaoguang Liu, Long Yu, Guangzhi Zhu, Hao Su, Xiangkun Wang, Wei Qin, Jianlong Deng, Xianmin Zeng, Xinping Ye, Tao Peng   +15 more
doaj   +1 more source

Development and validation of a robust immune-related prognostic signature in early-stage lung adenocarcinoma

Journal of Translational Medicine, 2020
Background The incidence of stage I and stage II lung adenocarcinoma (LUAD) is likely to increase with the introduction of annual screening programs for high-risk individuals. We aimed to identify a reliable prognostic signature with immune-related genes
Pancheng Wu, Yi Zheng, Yanyu Wang, Yadong Wang, Naixin Liang   +4 more
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Identification of a Four-Gene-Based SERM Signature for Prognostic and Drug Sensitivity Prediction in Gastric Cancer

Frontiers in Oncology, 2022
BackgroundGastric cancer (GC) is a highly molecular heterogeneous tumor with poor prognosis. Epithelial-mesenchymal transition (EMT) process and cancer stem cells (CSCs) are reported to share common signaling pathways and cause poor prognosis in GC ...
Xiya Jia, Xiya Jia, Bing Chen, Bing Chen, Ziteng Li, Ziteng Li, Shenglin Huang, Shenglin Huang, Siyuan Chen, Siyuan Chen, Runye Zhou, Runye Zhou, Wanjing Feng, Wanjing Feng, Hui Zhu, Hui Zhu, Xiaodong Zhu, Xiaodong Zhu   +17 more
doaj   +1 more source