Results 31 to 40 of about 101,985 (265)
Construction of a prognostic signature of autophagy-related lncRNAs in non-small-cell lung cancer
BMC Cancer, 2021 Background Autophagy inhibits tumorigenesis by limiting inflammation. LncRNAs regulate gene expression at various levels as RNAs; thus, both autophagy and lncRNAs are closely related to the occurrence and development of tumours.
Xinyang Zhang, Yu Cao, Li Chen
doaj +1 more source
Frontiers in Oncology, 2022 BackgroundThe key biochemical feature of malignant tumor is the conversion of energy metabolism from oxidative phosphorylation to glycolysis, which provides sufficient capacity and raw materials for tumor cell rapid growth.
Jiangdong Xiang +3 more
doaj +1 more source
Journal of Translational Medicine, 2019 Background The high mortality of patients with non-small cell lung cancer (NSCLC) emphasizes the necessity of identifying a robust and reliable prognostic signature for NSCLC patients.
Shuguang Zuo +6 more
doaj +1 more source
Comprehensive analysis reveals a metabolic ten-gene signature in hepatocellular carcinoma [PDF]
PeerJ, 2020 Background Due to the complicated molecular and cellular heterogeneity in hepatocellular carcinoma (HCC), the morbidity and mortality still remains high level in the world.
Zhipeng Zhu +6 more
doaj +2 more sources
Construction of lactylation-related prognostic signature for glioma. [PDF]
Discov OncolGlioma was a kind of malignant tumor associated with high mortality and recurrence. Therefore, it was urgent to establish effective prognostic models to guide clinical treatment in glioma. Protein lactylation was discovered in various malignant tumor, but only a few studies on glioma focused on protein lactylation.The expression levels of lactylation ...
Huang Y, Shi S, Yan Q, Qiu Z, Zeng Z.
europepmc +4 more sources
Thoracic Cancer, 2020 Background Local relapses and metastases are primary causes of death in lung cancer patients. In the present study, we aimed to develop a prognostic signature based on metastasis‐associated lncRNAs in patients with lung adenocarcinoma (LUAD).
Xiaoshi Zhang +12 more
doaj +1 more source
Prognostic stromal gene signatures in breast cancer [PDF]
Breast Cancer Research, 2015 Abstract Introduction Global gene expression analysis of tumor samples has been a valuable tool to subgroup tumors and has the potential to be of prognostic and predictive value. However, tumors are heterogeneous, and homogenates will consist of several different cell types.
Winslow, Sofia +3 more
openaire +2 more sources
Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma
Cancer Cell International, 2019 Background Hepatocellular carcinoma (HCC) remains a major challenge for public health worldwide. Considering the great heterogeneity of HCC, more accurate prognostic models are urgently needed.
Gao-Min Liu +3 more
doaj +1 more source
Development of Autophagy Signature‐Based Prognostic Nomogram for Refined Glioma Survival Prognostication [PDF]
BioMed Research International, 2020 The current glioma classification could be optimized to cover such a separate and individualized prognosis ranging from a few months to over ten years. Considering its highly conserved role and potential in therapies, autophagy might be a promising element to be incorporated as a refinement for improved survival prognostication.
Yuxiang Fan +3 more
openaire +2 more sources
Biochemistry and Biophysics ReportsPancreatic cancer is a lethal disease with a poor prognosis. Immunity and hypoxia are critical characteristics of the tumor microenvironment and are closely associated with cancer prognosis. The present study aimed to identify a novel hypoxia- and immune-
Ganghua Yang +7 more
doaj +1 more source