Results 31 to 40 of about 812,903 (257)
The 70-gene prognostic signature for korean breast cancer patients
, 2021 Purpose: A 70-gene prognostic signature has prognostic value in patients with node-negative breast cancer in Europe. This diagnostic test known as "Mamma PrintTM (70-gene prognostic signature)" was recently validated and ...
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core +1 more source
Thoracic Cancer, 2020 Background Local relapses and metastases are primary causes of death in lung cancer patients. In the present study, we aimed to develop a prognostic signature based on metastasis‐associated lncRNAs in patients with lung adenocarcinoma (LUAD).
Xiaoshi Zhang +12 more
doaj +1 more source
Identification of a six-gene signature predicting overall survival for hepatocellular carcinoma
Cancer Cell International, 2019 Background Hepatocellular carcinoma (HCC) remains a major challenge for public health worldwide. Considering the great heterogeneity of HCC, more accurate prognostic models are urgently needed.
Gao-Min Liu +3 more
doaj +1 more source
Biochemistry and Biophysics ReportsPancreatic cancer is a lethal disease with a poor prognosis. Immunity and hypoxia are critical characteristics of the tumor microenvironment and are closely associated with cancer prognosis. The present study aimed to identify a novel hypoxia- and immune-
Ganghua Yang +7 more
doaj +1 more source
Development and validation of an immune gene-set based prognostic signature for soft tissue sarcoma
BMC Cancer, 2021 Background Sarcomas is a group of heterogeneous malignant tumors originated from mesenchymal tissue and different types of sarcomas have disparate outcomes. The present study aims to identify the prognostic value of immune-related genes (IRGs) in sarcoma
Rui Shen +5 more
doaj +1 more source
BMC Medical Genetics, 2020 Background The prognosis of the glioblastoma (GBM) is dismal. This study aims to select an optimal RNA signature for prognostic prediction of GBM patients. Methods For the training set, the long non-coding RNA (lncRNA) and mRNA expression profiles of 151
Zhenyu Gong +4 more
doaj +1 more source
Identification of a prognostic six-immune-gene signature and a nomogram model for uveal melanoma
BMC Ophthalmology, 2023 Background To identify an immune-related prognostic signature and find potential therapeutic targets for uveal melanoma. Methods The RNA-sequencing data obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets.
Binghua Yang +4 more
doaj +1 more source
Development and internal validation of a nine-lncRNA prognostic signature for prediction of overall survival in colorectal cancer patients [PDF]
PeerJ, 2018 Background Colorectal cancer remains a serious public health problem due to the poor prognosis. In the present study, we attempted to develop and validate a prognostic signature to predict the individual mortality risk in colorectal cancer patients ...
Zhiqiao Zhang +7 more
doaj +2 more sources
Association Between a Prognostic Gene Signature and Functional Gene Sets
, 2008 Background The development of expression-based gene signatures for predicting prognosis or class membership is a popular and challenging task. Besides their stringent validation, signatures need a functional interpretation and must be placed in a ...
Klaus H. Metzeler +4 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source