Results 41 to 50 of about 101,985 (265)
Development and validation of an immune gene-set based prognostic signature for soft tissue sarcoma
BMC Cancer, 2021 Background Sarcomas is a group of heterogeneous malignant tumors originated from mesenchymal tissue and different types of sarcomas have disparate outcomes. The present study aims to identify the prognostic value of immune-related genes (IRGs) in sarcoma
Rui Shen +5 more
doaj +1 more source
Identification of a 9‐gene prognostic signature for breast cancer [PDF]
Cancer Medicine, 2020 AbstractBreast cancer (BRCA) is the most common cancer among women and is the second leading cause of cancer death in women. In this study, we developed a 9‐gene prognostic signature to predict the prognosis of patients with BRCA. GSE20685, GSE42568, GSE20711, and GSE88770 were used as training sets.
Zelin Tian +5 more
openaire +3 more sources
BMC Medical Genetics, 2020 Background The prognosis of the glioblastoma (GBM) is dismal. This study aims to select an optimal RNA signature for prognostic prediction of GBM patients. Methods For the training set, the long non-coding RNA (lncRNA) and mRNA expression profiles of 151
Zhenyu Gong +4 more
doaj +1 more source
An immune cell infiltration-related gene signature predicts prognosis for bladder cancer
Scientific Reports, 2021 To explore novel therapeutic targets, develop a gene signature and construct a prognostic nomogram of bladder cancer (BCa). Transcriptome data and clinical traits of BCa were downloaded from UCSC Xena database and Gene Expression Omnibus (GEO) database ...
Hualin Chen +3 more
doaj +1 more source
Identification and Validation of Prognostically Relevant Gene Signature in Melanoma [PDF]
BioMed Research International, 2020 Background. Currently, effective genetic markers are limited to predict the clinical outcome of melanoma. High‐throughput multiomics sequencing data have provided a valuable approach for the identification of genes associated with cancer prognosis. Method.
Yali Gao +7 more
openaire +2 more sources
Identification of a prognostic six-immune-gene signature and a nomogram model for uveal melanoma
BMC Ophthalmology, 2023 Background To identify an immune-related prognostic signature and find potential therapeutic targets for uveal melanoma. Methods The RNA-sequencing data obtained from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) datasets.
Binghua Yang +4 more
doaj +1 more source
Development and internal validation of a nine-lncRNA prognostic signature for prediction of overall survival in colorectal cancer patients [PDF]
PeerJ, 2018 Background Colorectal cancer remains a serious public health problem due to the poor prognosis. In the present study, we attempted to develop and validate a prognostic signature to predict the individual mortality risk in colorectal cancer patients ...
Zhiqiao Zhang +7 more
doaj +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Frontiers in Oncology, 2023 BackgroundMucinous adenocarcinoma (MAC) is a unique clinicopathological colorectal cancer (CRC) type that has been recognized as a separate entity from non-mucinous adenocarcinoma (NMAC), with distinct clinical, pathologic, and molecular characteristics.
An Huang +8 more
openaire +3 more sources
Development and Validation of a 9-Gene Prognostic Signature in Patients With Multiple Myeloma
Frontiers in Oncology, 2019 Background: Multiple myeloma (MM) is one of the most common types of hematological malignance, and the prognosis of MM patients remains poor.Objective: To identify and validate a genetic prognostic signature in patients with MM.Methods: Co-expression ...
Xiao-Ping Liu +5 more
doaj +1 more source