Results 71 to 80 of about 3,771,203 (333)

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Synthesis, Characterization and Fabrication of Copper Nanoparticles Embedded Non-Perfluorintaed Kraton Based Ionic Polymer Metal Composite (IPMC) Actuator

Actuators, 2022
Recently, cost-effective ionic polymer metal composite (IPMC) membranes coated with novel metals (viz., Ag, Au, or Pt) have exhibited excellent bending actuation performance, which was electrically stimulated.
Mohammad Luqman, Arfat Anis, Hamid M. Shaikh, Saeed M. Al-Zahrani, Mohammad Asif Alam   +4 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Characterization and Analysis of Extensile Fluidic Artificial Muscles

Actuators, 2021
Extensile fluidic artificial muscles (EFAMs) are soft actuators known for their large ranges of extension, low weight, and blocked forces comparable to those of pneumatic cylinders.
Jacek Garbulinski, Sai C. Balasankula, Norman M. Wereley   +2 more
doaj   +1 more source

On Neuromechanical Approaches for the Study of Biological Grasp and Manipulation

, 2017
Biological and robotic grasp and manipulation are undeniably similar at the level of mechanical task performance. However, their underlying fundamental biological vs.
Santello, Marco, Valero-Cuevas, Francisco J   +1 more
core   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Finger Prosthesis Driven by DEA Pairs as Agonist–Antagonist Artificial Muscles

Biomimetics
Loss of an upper limb exerts a negative influence on an individual’s ability to perform their activities of daily living (ADLs), reducing quality of life and self-esteem.
Alexandre B. S. da Silva, Gabriel E. P. Mendes, Eduardo S. Bragato, Guilherme L. Novelli, Marina Monjardim, Rafhael M. Andrade   +5 more
doaj   +1 more source

Enhanced Ionic Polymer–Metal Composites with Nanocomposite Electrodes for Restoring Eyelid Movement of Patients with Ptosis

Nanomaterials, 2023
The present study aims to use enhanced ionic polymer–metal composites (IPMC) as an artificial muscle (a soft-active actuator) to restore eyelid movement of patients with ptosis. The previous eyelid movement mechanisms contained drawbacks, specifically in
Sara Sadat Hosseini, Bakhtiar Yamini, Levan Ichkitidze, Majid Asadi, Julie Fernandez, Seifollah Gholampour   +5 more
doaj   +1 more source

Fluid muscle behavior determination [PDF]

, 2014
Táto práca sa zaoberá zistením základných charakteristík pneumatického umelého svalu PAM (Pneumatic artificial muscle) firmy Festo, programovaním knižnice prvkov v prostredí LabVIEW pre proporcionálne ovládanie ventilu, návrhom a zostrojením stanice pre ...
Szente, Michal
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source