Results 121 to 130 of about 34,934 (250)

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source

Patient-specific deep offline artificial pancreas for blood glucose regulation in type 1 diabetes. [PDF]

Smart Health (Amst)
Deng Y, Arao K, Mantzoros CS, Karniadakis GE.   +3 more
europepmc   +1 more source

The Artificial Pancreas and Type 1 Diabetes.

J Clin Endocrinol Metab, 2023
Nwokolo M, Hovorka R.
europepmc   +1 more source

Control of blood glucose levels by an artificial pancreas in patients with severe coronavirus disease 2019 pneumonia. [PDF]

Artif Organs, 2023
Tokuhira N, Uchiyama A, Hoshino T, Kubo N, Ishigaki S, Enokidani Y, Sakaguchi R, Koyama Y, Fujino Y.   +8 more
europepmc   +1 more source

Engineering Lipid Nanoparticles for Precision RNA Delivery: Design Principles, Targeting Strategies, and Clinical Prospects

Cancer Nexus, EarlyView.
ABSTRACT Lipid nanoparticles (LNPs) represent the most clinically advanced platform for RNA delivery and have enabled major breakthroughs in vaccines and gene therapies. However, their broader application is still limited by inefficient extrahepatic delivery, immunogenicity, and insufficient control over tissue‐ and cell‐specific targeting. This review
Yu Han, Ying Wang, Xintao Gao, Yan Lei, Yantao Li, Zhiyong Tang   +5 more
wiley   +1 more source

A sensor-fault resilient artificial pancreas using type-3 fuzzy logic and predictive controls. [PDF]

Sci Rep
Mai VT, Alattas KA, Khani A, Mohammadzadeh A.   +3 more
europepmc   +1 more source

Lactate receptor HCAR1 in neonatal hypoxic–ischemic seizures

Epilepsia, EarlyView.
Abstract Hydroxycarboxylic acid receptor 1 (HCAR1) is a G‐protein‐coupled lactate receptor expressed in the brain and plays a role in neuronal excitability and repair after injury. Hypoxic–ischemic encephalopathy (HIE) is the most common cause of brain injury and seizures in term neonates.
Jennifer Burnsed, Angelina June, Maria Marlicz, Emmy Zucker, Ellie Kain‐Kuzniewski, Hannah Mulhern, Leanne Maharaj, John Williamson, Chengsan Sun, Suchitra Joshi, Huayu Sun, Jaideep Kapur   +11 more
wiley   +1 more source

Initiation of Hybrid Closed-Loop Artificial Pancreas System Improves Glycemic Control in a Hospitalized Type 1 Diabetes: A Case Report and Review. [PDF]

Case Rep Endocrinol
Li S, Lv P, Lu H, Liu Y, Shen Y, Cai C, Zeng X, Lu H, Zhao Y.   +8 more
europepmc   +1 more source

In silico design and validation of a time-varying PID controller for an artificial pancreas with intraperitoneal insulin delivery and glucose sensing. [PDF]

APL Bioeng, 2023
Dalla Libera A, Toffanin C, Drecogna M, Galderisi A, Pillonetto G, Cobelli C.   +5 more
europepmc   +1 more source

Micro Pattern‐Based 3D Cell Culture Platform: An Overview of Technologies and Applications

Exploration, EarlyView.
Micro patterns are characterized as a coating of specific adhesion matrices on substrates to support cell growth. An overview of micropattern technology to regulate single cell morphology and fates, further focusing on the micro pattern‐based 3D cell culture platform used in the non‐tumor and tumor researches.
Xinglong Zhu, Yi Li, Hulin Long, Yijia Wu, Ningwei Sun, Shun Li, Yiyao Liu, Huiqi Xie, Ji Bao   +8 more
wiley   +1 more source