Results 201 to 210 of about 36,803 (257)

Pancreatic Cancer—Advances in the Last 50 Years

open access: yes
World Journal of Surgery, EarlyView.
S. George Barreto   +5 more
wiley   +1 more source

Clustering of technological attitudes and reasons for device (non‐)uptake among Dutch people with type 1 diabetes, family members and health professionals

open access: yesDiabetic Medicine, EarlyView.
Abstract Background Pump and sensor technology contributes to glucose management and quality of life for people with type 1 diabetes (PWD). However, not everyone uses these technologies. This commonly relates to technological attitudes, experiences and expectations. Also, parents and partners (P/P) and healthcare providers (HCPs) may impactful decision‐
M. Horsselenberg   +4 more
wiley   +1 more source

Extracellular matrix and proteolysis: mechanisms driving irreversible changes and shaping cell behavior

open access: yesThe FEBS Journal, EarlyView.
Irreversible ECM proteolysis by remodeling enzymes shapes development, homeostasis, and disease. ECM‐degrading proteases display cell specificity and are governed by shared mechanisms, exhibiting functional redundancy in generating matrikines, growth factors, and cytokines.
Inna Solomonov, Orit Kollet, Irit Sagi
wiley   +1 more source

ALDH2 Polymorphism in Alcohol‐Related Cirrhosis Requiring Liver Transplantation: A Recipient–Donor Analysis

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim Genetic polymorphisms of alcohol‐metabolizing enzymes influence drinking behavior and susceptibility to alcohol‐related liver disease (ALD). This study aimed to clarify the distribution of ALDH2 and ADH1B genotypes in liver transplant recipients with ALD, and to explore associations with post‐transplant drinking behavior using a recipient ...
Noriyo Yamashiki   +3 more
wiley   +1 more source

Benign by design: A paradigm shift in cosmetic ingredient development

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Benign by design strategies enable the creation of biodegradable cosmetic ingredients, reducing environmental persistence while maintaining the intended biological activity. This work compiles design rules and tools to guide the development of more sustainable molecules for the cosmetics industry.
Sandra Mota   +3 more
wiley   +1 more source

Circadian Deregulation in Multiple Myeloma: BMAL1/CLOCK Expression Patterns and Diagnostic Performance

open access: yesInternational Journal of Laboratory Hematology, EarlyView.
ABSTRACT Background Circadian clock disruption has emerged as a relevant axis in cancer; however, the expression patterns and diagnostic relevance of BMAL1 and CLOCK in multiple myeloma (MM) remain insufficiently defined. Methods BMAL1 and CLOCK mRNA expression was quantified by RT‐qPCR in bone marrow samples from 46 newly diagnosed MM patients and 13 ...
Hamide Albayrak   +6 more
wiley   +1 more source

Hybrid Closed Loop Using a Do-It-Yourself Artificial Pancreas System in Adults With Type 1 Diabetes. [PDF]

open access: yesJ Diabetes Sci Technol
Nanayakkara N   +5 more
europepmc   +1 more source

The Artificial Pancreas

Artificial Cells, Blood Substitutes, and Biotechnology, 2003
In type 1 diabetes an absolute deficiency of insulin secretion requires exogenous insulin supply to guarantee the patient's life avoiding ketoacidotic coma and to prevent the chronic complications of diabetes. In order to obtain a more physiological replacement therapy different approaches have been pursued since the early 70s to create an artificial ...
Paolo, Brunetti   +2 more
openaire   +2 more sources

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