Results 121 to 130 of about 80,289 (279)

2D Copper MOF Membranes with Precise Pores for Ionic Memory

open access: yesAdvanced Science, EarlyView.
 . ABSTRACT Biological ion channels play a critical role in the complex physiological processes of living organisms. Inspired by these natural systems, we demonstrate the fabrication of ultrathin 2D copper‐based metal‐organic framework (CuMOF) films and their application to mimic key functionalities of biological membranes. Using a liquid–air interface
Hiran Jyothilal   +9 more
wiley   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

open access: yesAdvanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun   +11 more
wiley   +1 more source

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

open access: yesAdvanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu   +11 more
wiley   +1 more source

Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain

open access: yesAdvanced Science, EarlyView.
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio   +3 more
wiley   +1 more source

An Artificial Synapse Based on CsPbI3 Thin Film. [PDF]

open access: yesMicromachines (Basel), 2022
Chen JY   +5 more
europepmc   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

open access: yesAdvanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu   +9 more
wiley   +1 more source

Neurorobotic approaches to emulate human motor control with the integration of artificial synapse. [PDF]

open access: yesSci Adv, 2022
Kim S   +10 more
europepmc   +1 more source

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