Results 31 to 40 of about 139,371 (207)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

The Source of Lake Wobegon [updated]

open access: yesNonpartisan Education Review, 2010
John J. Cannell's late 1980's "Lake Wobegon" reports suggested widespread deliberateeducator manipulation of norm-referenced standardized test (NRT) administrations and results,resulting in artificial test score gains.
Richard P. Phelps
doaj  

Multimodal Large Language Models for Cystoscopic Image Interpretation and Bladder Lesion Classification: Comparative Study

open access: yesJournal of Medical Internet Research
BackgroundCystoscopy remains the gold standard for diagnosing bladder lesions; however, its diagnostic accuracy is operator dependent and prone to missing subtle abnormalities such as carcinoma in situ or misinterpreting mimic ...
Yung-Chi Shih   +3 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

A Tribute to John J. Cannell, M.D.

open access: yesNonpartisan Education Review, 2006
no ...
Richard P. Phelps
doaj  

Mapping Mutual Fund Investor Characteristics and Modeling Switching Behavior [PDF]

open access: yes, 2003
Securing a mutual fund that meets investment goals is an important reason why some investors exclusively stay with a particular mutual fund and others switch funds within their fund family.
Akhter, Syed H.   +2 more
core   +1 more source

Learning to Identify Ambiguous and Misleading News Headlines

open access: yes, 2017
Accuracy is one of the basic principles of journalism. However, it is increasingly hard to manage due to the diversity of news media. Some editors of online news tend to use catchy headlines which trick readers into clicking.
Wan, Xiaojun, Wei, Wei
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Dan Koretz's Big Con

open access: yesNonpartisan Education Review, 2017
no ...
Richard P. Phelps
doaj  

Deep learning ensemble models for CT-based differentiation of malignant and benign sacral bone tumors: development and evaluation

open access: yesInsights into Imaging
Objective Radiologists often face challenges in differentiating benign from malignant sacral bone lesions due to their similar imaging characteristics. This study aimed to develop an ensemble deep learning (DL) model that can preoperatively distinguish ...
Ping Yin   +8 more
doaj   +1 more source

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