Results 41 to 50 of about 134,090 (205)

Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda [PDF]

, 2010
Prevention of mother-to-child transmission (PMTCT) is essential in HIV/AIDS control. We analysed 2000-05 data from mother-infant pairs in our PMTCT programme in rural Uganda, examining programme utilization and outcomes, HIV transmission rates and ...
Ahoua, Laurence, Ayikoru, Harriet, Balkan, Suna, Gnauck, Katherine, Odar, Emmanuel, Odaru, Grace, Olson, David, Ondoa-Onama, Christine, Pinoges, Loretxu, Pujades-Rodríguez, Mar   +9 more
core   +2 more sources

Potential contribution of biomass gasification‐based technology in energy transition: a technical review coupled with bibliometric studies

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Biomass gasification technology has been extensively researched around the world; however, there is a need to evaluate the current research landscape and evolutionary direction of research in the broader context of energy transition. A systematic bibliometric analysis of the Web of Science database was performed for articles that fall within ...
Olasunkanmi Opeoluwa Adeoye, Electo Eduardo Silva Lora, Rubenildo Vieira Andrade, Leonardo Peña Pupo, René Lesme Jaén, Osvaldo José Venturini   +5 more
wiley   +1 more source

Evaluation of valve function in antireflux biliary metal stents

BMC Gastroenterology, 2018
Background To overcome duodenobiliary reflux induced by biliary stents, antireflux valve (ARV) biliary stents have been developed and showed improvement in stent patency.
Chang-Il Kwon, Jong Pil Moon, Ho Yun, Seok Jeong, Dong Hee Koh, Woo Jung Lee, Kwang Hyun Ko, Dae Hwan Kang   +7 more
doaj   +1 more source

Physiologically based pharmacokinetic model combined with a clinical lactation study to determine doravirine concentrations in human breastmilk

British Journal of Clinical Pharmacology, EarlyView.
Aims To determine breastmilk concentrations of doravirine via PBPK modelling in combination with a clinical lactation study. As women living with HIV are not able to cease antiretroviral therapy during lactation, it is necessary to establish drug transfer into breastmilk to determine exposure of the infant to antiretroviral drugs and potential risk of ...
Lena van der Wekken‐Pas, David Burger, Rick Greupink, Angela Colbers   +3 more
wiley   +1 more source

Efficient Preparation of Homogenous Antibody Conjugates via Glycosite‐Specific Transglycosylation Enabled by Readily Available Glycosyl Donors

Angewandte Chemie, Volume 138, Issue 7, 9 February 2026.
A streamlined platform for glycosite‐specific antibody conjugation is enabled by LacNAc‐derived cyclic acetal donors, which can be prepared in only two steps and used directly in single‐enzyme Endo S2‐mediated transglycosylation. The platform supports the broad construction of homogeneous gsADCs and gsDACs, with donor 7 producing glycoengineered ...
Deqin Cai, Yuan Zhao, Gaoyuan Lu, Chunrong Li, Yichong Lao, Ramesh Mudududdla, Jiahao Zhang, Peijing Jia, Penghsuan Huang, Wenxin Wu, Thao‐Vy T. Nguyen, Xuhui Huang, Lingjun Li, Weiping Tang   +13 more
wiley   +2 more sources

The 96-week outcomes and pharmacokinetics of long-acting cabotegravir plus rilpivirine in South Africans

Southern African Journal of HIV Medicine
Background: Evaluating long-term efficacy, safety and pharmacokinetics of long-acting cabotegravir + rilpivirine (CAB+RPV LA) in sub-Saharan African populations is important because of the region’s unique demographics and antiretroviral therapy ...
Rosie Mngqibisa, Yashna Singh, Catherine Orrell, Johan Lombaard, Sandy Griffith, Conn Harrington, Ronald D’Amico, William Spreen, Marty St Clair, Christine Latham, Louise Garside, Rodica Van Solingen-Ristea, Veerle Van Eygen, Fafa Addo Boateng, Herta Crauwels, Prosperity Eneh, Ingrid Eshun-Wilsonova   +16 more
doaj   +1 more source

Using cost-effectiveness analyses to inform policy: the case of antiretroviral therapy in Thailand. [PDF]

, 2006
BACKGROUND: Much emphasis is put on providing evidence to assist policymakers in priority setting and investment decisions. Assessing the cost-effectiveness of interventions is one technique used by policymakers in their decisions around the allocation ...
Tantivess, Sripen, Walt, Gill
core   +2 more sources

A Facile Protocol for C(sp2)–C(sp3) Bond Formation Reactions Toward Functionalized E3 Ligase Ligands

ChemMedChem, EarlyView.
A robust C(sp2)–C(sp3) decarboxylative coupling strategy enables access to new CRBN ligands and degraders with improved physicochemical properties. This synthetic approach is expanding the chemical space beyond C(sp2)–N linkages, fine‐tuning proteolysis‐targeting chimera activities and unlocking previously inaccessible degrader chemotypes.
Anita Maksutova, Thomas M. Geiger, Lorenzo Cianni, Dominika E. Pieńkowska, Jan Gerhartz, Lina Read, Aleša Bricelj, Alexander Herrmann, Maurice Leon Nelles, Yuen Lam Dora Ng, Marcus D. Hartmann, Jan Krönke, Izidor Sosič, Radosław P. Nowak, Michael Gütschow, Christian Steinebach   +15 more
wiley   +1 more source

U.S. Strategy for Rapid Scale-Up of ARV Treatment: Advocacy Issues and Concerns [PDF]

, 2003
Provides background on international developments concerning anti-retroviral drugs (ARV) and related U.S. policy, and summarizes the presentations and recommendations of representatives from organizations providing ARV treatment in developing ...

core  

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source