Results 61 to 70 of about 22,237 (159)

Understanding the Potential of Antibody‐Drug Conjugates Functionalized Engineered Exosomes in Hepatocellular Carcinoma Therapy: A Comprehensive Narrative Review

Health Science Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Exosomes are naturally secreted nanovesicles with high biocompatibility, low immunogenicity, and the ability to traverse biological barriers, making them attractive theragnostic carriers. When engineered to present tumor‐specific antibodies and to deliver antibody‐drug conjugates (ADCs), they may enhance selective targeting of ...
Subham Sarkar, Avinaba Bose, Jenifer Rajak, Arup Kumar Mitra, Ajoy Kumer, Bikram Dhara   +5 more
wiley   +1 more source

Seroprevalence of anti-SARS-CoV-2 IgG antibodies among children attending the pediatric hospital in Bamako, Mali (BamaCoV-Kids Study)

BMC Infectious Diseases
Background This study aimed to assess the seroprevalence of SARS-CoV-2 among children attending pediatric consultations in Bamako, Mali, using a rapid diagnostic test (RDT) on fingertip or venous blood samples.
Almoustapha Issiaka Maiga, Amadou Kodio, Salimata Alou Ouedraogo, Aliou Baldé, Penda Dembele, Fatoumata Tata Traore, Oumar Dolo, Josué Togo, Yacouba Aba Coulibaly, Mariam Sylla, Robert L. Murphy, Anne-Geneviève Marcelin, Vincent Calvez, Abdoul Aziz Diakité, Eve Todesco   +14 more
doaj   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Characterisation of HIV‐1 Gag Cytotoxic T‐Lymphocyte Epitopes in the Southern African Region—A Systematic Review

Immunology, Volume 179, Issue 2, Page 165-184, October 2026.
Distribution of studies on HIV‐1 Gag cytotoxic T‐lymphocyte epitopes in the southern African region showing that the majority of studies (58.44%) were conducted in South Africa, followed by Botswana (15.58%), Zambia (10.39%), Malawi (7.79%), Zimbabwe (6.49%), and Angola (1.30%).
Tumelo L. Fortuin, Paballo Nkone, Shayne Loubser, Caroline T. Tiemessen, Simnikiwe H. Mayaphi   +4 more
wiley   +1 more source

Pengaruh Pendidikan Dan Pekerjaan Orangtua Dengan Tingkat Kepatuhan ARV Pada Anak HIV/AIDS

Citra Delima, 2019
Terapi Antiretroviral (ARV) merupakan sesuatu pengobatan pada HIV/AIDS, tetapi ketidak tahuan mereka akan informasi yang berkaitan dengan terapi antiretroviral (ARV) akan menimbulkan ketidak patuhan konsumsi obat (ARV).
Zainal Munir, Fendi Romadoni
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, Volume 20, Issue 9, Page 2340-2355, September 2026.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Oncolytic avian reovirus-sensitized tumor infiltrating CD8+ T cells triggering immunogenic apoptosis in gastric cancer

Cell Communication and Signaling
Background Gastric cancer (GC) is a leading malignant disease in numerous countries, including Taiwan with limited therapeutic options. Animal viruses including oncolytic avian reovirus (ARV) have the possibility to avoid pre-existing immunity in humans,
Yi-Ying Wu, Feng-Hsu Wu, I-Chun Chen, Tsai-Ling Liao, Muhammad Munir, Hung-Jen Liu   +5 more
doaj   +1 more source

Autophagy induced by avian reovirus enhances viral replication in chickens at the early stage of infection

BMC Veterinary Research, 2019
Background Avian reovirus (ARV) is an important pathogen that can cause serious disease in poultry. Though several in vitro studies revealed some molecular mechanisms that are responsible for ARV-induced autophagy, it is still largely unknown how ARV ...
Xiaosai Niu, Chengcheng Zhang, Yuyang Wang, Mengjiao Guo, Baoyang Ruan, Xuefeng Wang, Tianqi Wu, Xiaorong Zhang, Yantao Wu   +8 more
doaj   +1 more source

Kidney function and brain health: cognitive and structural signatures across cohorts

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION Chronic kidney disease (CKD) is linked to cognitive decline, yet the roles of estimated glomerular filtration rate (eGFR) and its variability remain unclear. METHODS We analyzed 6847 adults from two population‐based cohorts (the Multimodality MEdical imaging sTudy bAsed on KaiLuan Study [META‐KLS], UK Biobank) and 426 CKD patients
Min Li, Wenbo Yang, Ying Hui, Huijing Shi, Yuntao Wu, Li Yu, Lijun Song, Yanfang Tan, Xintian Ren, Xiaoyan Bai, Xiaoshuai Li, Zhenghan Yang, Weikang Guo, Shouling Wu, Jing Li, Zhenchang Wang, Han Lv, Hao Wang   +17 more
wiley   +1 more source

Construction of recombinant Marek’s disease virus co-expressing σB and σC of avian reoviruses

Frontiers in Veterinary Science
Avian reoviruses (ARVs) cause viral arthritis or tenosynovitis, resulting in poor weight gain and increased feed conversion ratios in chickens. In this study, we generated three Marek’s disease virus (MDV) recombinants, namely, rMDV-ARV-σB, rMDV-ARV-σC ...
Li Gao, Li Gao, Li Zhong, Yongzhen Liu, Changjun Liu, Yanping Zhang, Hongyu Cui, Xiaole Qi, Jiayong Zhang, Jia Xu, Suyan Wang, Yuntong Chen, Yulu Duan, Kai Li, Kai Li, Kai Li, Yulong Gao, Xiaomei Wang, Xiaomei Wang   +18 more
doaj   +1 more source