Results 61 to 70 of about 134,090 (205)

Sigma1 Targeting to Suppress Aberrant Androgen Receptor Signaling in Prostate Cancer. [PDF]

, 2017
Suppression of androgen receptor (AR) activity in prostate cancer by androgen depletion or direct AR antagonist treatment, although initially effective, leads to incurable castration-resistant prostate cancer (CRPC) via compensatory mechanisms including ...
Anderson, Kelsey N., Chen, Nan, Kania, Blase, Kim, Felix J., Knudsen, Karen E., Longen, Charles G., Maher, Christina M., Ostrander, William F., Oyer, Halley M., Salvino, Joseph M., Thomas, Jeffrey D.   +10 more
core   +1 more source

Insufficient access to harm reduction measures in prisons in 5 countries (PRIDE Europe): a shared European public health concern [PDF]

, 2015
Background: Prisoners constitute a high-risk population, particularly for infectious diseases. The aim of this study was to estimate the level of infectious risk in the prisons of five different European countries by measuring to what extent the prison ...
Brentari, Cinzia, Holm, Karina, Jauffret-Roustide, Marie, Kolind, Torsten, Lion, Caroline, M Carrieri, Patrizia, Maguet, Olivier, Michel, Laurent, Moser, Andrea, Nava, Felice, Schiltz, Julie, Stöver, Heino, Van Malderen, Sara, Vanderplasschen, Wouter, Weltzien, Nadja   +14 more
core   +5 more sources

Exploring the impact of baseline and on‐treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study

HIV Medicine, EarlyView.
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
M. Gartland, X. Wang, Q. Liao, B. Li, F. Du, M. Krystal, A. R. Tenorio, A. Pierce, J. R. Castillo‐Mancilla   +8 more
wiley   +1 more source

Predictors of early mortality and effectiveness of antiretroviral therapy in TB-HIV patients from Brazil.

PLoS ONE, 2019
BackgroundThe implementation of antiretroviral (ARV) therapy caused a significant decrease in HIV-associated mortality worldwide. Nevertheless, mortality is still high among people living with HIV/AIDS and tuberculosis (TB).
Fernanda O Demitto, Carolina A S Schmaltz, Flávia M Sant'Anna, María B Arriaga, Bruno B Andrade, Valeria C Rolla   +5 more
doaj   +1 more source

Effectiveness and safety of two‐drug regimens containing an integrase inhibitor and reverse transcriptase inhibitor in a cohort of virologically suppressed people with HIV: Data from the COMBINE‐2 study

HIV Medicine, EarlyView.
Abstract Objectives This study assessed real‐world effectiveness and safety of switching to dual therapy regimens consisting of an integrase inhibitor (INSTI), and reverse transcriptase inhibitor (RTI), among suppressed people living with HIV in Europe.
Cristina Mussini, Cassidy Henegar, Lambert Assoumou, Stephane de Wit, Margaret Johnson, Eugenia Quiros‐Roldan, Chris Kenyon, Colin Deschanvres, David Zucman, Frank Post, Roya Movahedi, Laura Comi, Julie Fox, Geoffrey Liegeon, Charlotte Martin, Jonathan Edwards, Giorgio Tiecco, Marc Delforge, Leigh Ragone, Bryn Jones, Jean van Wyk, Michael Aboud, Carl Fletcher, Anton Pozniak, Vani Vannappagari   +24 more
wiley   +1 more source

AIDS Treatment and Intrahousehold Resource Allocations: Children's Nutrition and Schooling in Kenya [PDF]

The provision of life-saving antiretroviral (ARV) treatment has emerged as a key component of the global response to HIV/AIDS, but very little is known about the impact of this intervention on the welfare of children in the households of treated persons.
Harsha Thirumurthy, Joshua S. Graff Zivin, Markus Goldstein   +2 more
core   +3 more sources

The Trust‐Link Relational Transition Model: A Unitary Caring Framework for Youth With HIV Transitioning to Adult Healthcare

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To develop a conceptual model integrating Robinson's Theory of Trust and Watson's Caritas Processes to guide trust‐building approaches and caring practices that support adolescents and young adults with HIV during the healthcare transition from paediatric to adult care.
Emily Anne Barr, Sara Horton‐Deutsch
wiley   +1 more source

Step-like discontinuities in Bose-Einstein condensates and Hawking radiation: dispersion effects [PDF]

, 2010
In this paper we extend the hydrodynamic results of [1] and study, analytically, the propagation of Bogoliubov phonons on top of Bose-Einstein condensates with step-like discontinuities by taking into account dispersion effects.
Fabbri, Alessandro, Mayoral, Carlos, Rinaldi, Massimiliano   +2 more
core   +5 more sources

A Case‐Control Investigation of Factors Associated With Risky Sexual Behaviors Among South African University Students

Public Health Nursing, EarlyView.
ABSTRACT Objective This study aimed to investigate risk factors associated with risky sexual behaviors (RSBs) and HIV seropositivity among students from four universities in KwaZulu‐Natal, South Africa. Design A case‐control methodology was used. Sample The sample consisted of 500 students (375 HIV negative students and 125 students living with HIV ...
Trishka Pillay, Nalini Govender, Poovendhree Reddy   +2 more
wiley   +1 more source

Primary local wound management practices and initiation of post-exposure prophylaxis among animal bite victims in a teaching institution hospital of Central India

Journal of Family Medicine and Primary Care
Context: Rabies is associated with sociocultural practices and myths leading to ineffective management of wound due to animal bite among the victims making it prime importance in the field of primary health care.
Arindam Maiti, Arvind Sharma, Sunita Patel, Ashish Mishra   +3 more
doaj   +1 more source