Results 1 to 10 of about 7,895 (187)

High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies. [PDF]

open access: yesPLoS ONE, 2011
Genetic investigations of X-linked intellectual disabilities have implicated the ARX (Aristaless-related homeobox) gene in a wide spectrum of disorders extending from phenotypes characterised by severe neuronal migration defects such as lissencephaly, to
Marie-Lise Quillé   +11 more
doaj   +1 more source

FCoR-Foxo1 Axis Regulates α-Cell Mass through Repression of Arx Expression

open access: yesiScience, 2020
Summary: Pancreatic endocrine cell development into differentiated α- and β-cells is highly regulated and involves multiple transcription factors. However, the mechanisms behind the determination of α- and β-cell masses remains unclear.
Noriko Kodani   +5 more
doaj   +1 more source

Узы. Парадигмы Рая. Огюст Роден и Ансельм Кифер

open access: yesИскусство Евразии, 2018
Статья представляет собой обзор и анализ выставки работ О. Родена и А. Кифера в 2017 году в музее Огюста Родена в Париже. Отправной точкой выставки послужил труд «Соборы Франции», а сама экспозиция стала диалогом двух художников, выразив сближение двух ...
Ковалева-Милорадович, Анна Эдуардовна
doaj   +1 more source

Regulating transcriptional activity by phosphorylation: A new mechanism for the ARX homeodomain transcription factor. [PDF]

open access: yesPLoS ONE, 2018
Aristaless-related homeobox (ARX) gene encodes a paired-type homeodomain transcription factor with critical roles in development. Here we identify that ARX protein is phosphorylated.
Tessa Mattiske   +6 more
doaj   +1 more source

Deep Learning-Based State-Dependent ARX Modeling and Predictive Control of Nonlinear Systems

open access: yesIEEE Access, 2023
For many practical industrial objects with time-varying operating points, strong nonlinearity, and difficulty in obtaining analytical models, the data-driven identification method is usually used to model such nonlinear systems.
Tiao Kang   +4 more
doaj   +1 more source

Aristaless Related Homeobox (ARX) Interacts with β-Catenin, BCL9, and P300 to Regulate Canonical Wnt Signaling. [PDF]

open access: yesPLoS ONE, 2017
Mutations in the Aristaless Related Homeobox (ARX) gene are associated with a spectrum of structural (lissencephaly) and functional (epilepsy and intellectual disabilities) neurodevelopmental disorders.
Il-Taeg Cho   +3 more
doaj   +1 more source

Using carry-truncated addition to analyze add-rotate-xor hash algorithms

open access: yesJournal of Mathematical Cryptology, 2013
We introduce a truncated addition operation on pairs of N-bit binary numbers that interpolates between ordinary addition mod and bitwise addition in . We use truncated addition to analyze hash functions that are built from the bit operations add, rotate,
Field Rebecca E., Jones Brant C.
doaj   +1 more source

Arx expansion mutation perturbs cortical development by augmenting apoptosis without activating innate immunity in a mouse model of X-linked infantile spasms syndrome

open access: yesDisease Models & Mechanisms, 2020
X-linked infantile spasms syndrome (ISSX) is a clinically devastating developmental epileptic encephalopathy with life-long impact. Arx(GCG)10+7, a mouse model of the most common triplet-repeat expansion mutation of ARX, exhibits neonatal spasms ...
Meagan S. Siehr   +2 more
doaj   +1 more source

Use several tests on the residual with control panel X to diagnose equation error models [PDF]

open access: yesمجلة التربية والعلم, 2018
In this research several models were matched of dynamic linear systems of the equation error models which included ARMAX and ARX  and applied using stationary  on a series of inputand output series.
Helaaa Abdulmajeed
doaj   +1 more source

Postnatal Arx transcriptional activity regulates functional properties of PV interneurons

open access: yesiScience, 2021
Summary: The transcription factor Aristaless-related X-linked gene (Arx) is a monogenic factor in early onset epileptic encephalopathies (EOEEs) and a fundamental regulator of early stages of brain development.
Donald J. Joseph   +8 more
doaj   +1 more source

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