Results 91 to 100 of about 2,826 (138)

Subcellular localization of human placental aryl hydrocarbon hydroxylase

Toxicology and Applied Pharmacology, 1973
Abstract Homogenates of human placentas were fractionated by a variety of differential centrifugation techniques. Prepared subfractions were assayed by ultrastructure analysis and marker enzyme quantitation. The lowest ratios of cytochrome oxidase/aryl hydrocarbon hydroxylase activities were observed in a 6.24 × 10 6 g -min sediment fraction ...
M R, Juchau, E A, Smuckler
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Pulmonary Carcinogenesis: Aryl Hydrocarbon Hydroxylase

1981
Especially during the past two decades, there has been a growing awareness that exposure of individuals to exogenous environmental agents is responsible for various kinds of cancer. Chemical carcinogenesis in man was first documented in 1775 by the British physician Percival Pott, who attributed the high incidence of scrotal cancer in London chimney ...
Theodore L. McLemore, R. Russell Martin
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Aryl hydrocarbon hydroxylase in persons with lung or laryngeal cancer

International Journal of Cancer, 1978
AbstractTo test whether the distribution of AHH inducibility is shifted toward the high end of the range in patients who had lung and laryngeal cancer, we measured this trait in 59 patients (32 lung and 27 laryngeal) who had resectable tumors and had been disease‐free for a period of time.
Ward, E, Paigen, B, Steenland, K, Vincent, R, Minowada, J, Gurtoo, H L, Sartori, P, Havens, M B   +7 more
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Aryl hydroxylase induction in the chick embryo by polycyclic hydrocarbons

Biochimica et Biophysica Acta (BBA) - General Subjects, 1973
Abstract The ability of various polycyclic hydrocarbons to induce liver microsomal enzzmes which convert 7,12-[ 14 C ] dimethylbenz (a) anthracene to water-soluble products was compared in the chick embryo and the rat. A good correlation in response to the 18 hydrocarbons tested was obtained but the chick embryo was found to provide a
P H, Jellinck, G, Smith
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Aryl Hydrocarbon Hydroxylase Activity in Rat Submandibular Glands

Journal of Dental Research, 1986
The activities of aryl hydrocarbon hydroxylase and 7-ethoxycoumarin O-de-ethylase in the rat submandibular gland, both of which are normally very low, were increased about 10- and 25-fold, respectively, by administration of 3-methylcholanthrene.
K, Murakami, T, Ishikawa, T, Shimosato, M, Noshiro, S, Hayashi, K, Okuda   +5 more
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Induction of aryl hydrocarbon hydroxylase activity and pulmonary carcinoma

International Journal of Cancer, 1979
AbstractAryl hydrocarbon hydroxylase activity in lymphoblasts from normal Finnish adults and from patients with pulmonary carcinomas and other types of malignancy has been studied by a modification of previously used techniques. High absolute induced aryl hydrocarbon hydroxylase activity was found in 39% of patients with untreated lung cancer but only ...
C G, Gahmberg, A, Sekki, T U, Kosunen, L R, Holsti, O, Mäkelä   +4 more
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Placental aryl hydrocarbon hydroxylase activity and placental calcifications

Toxicology, 1992
Induction of aryl hydrocarbon hydroxylase (AHH) activity in the placenta as a result of maternal exposure to polycyclic aromatic hydrocarbons contained in cigarette smoke has been well documented. Furthermore, calcifications are more prevalent in the placentas of pregnant smokers than in those of non-smokers.
G, Huel, F, Girard, C, Nessmann, J, Godin, P, Blot, G, Bréart, T, Moreau   +6 more
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Nuclear aryl hydrocarbon hydroxylase and interaction of polycyclic hydrocarbons with nuclear components

Archives of Biochemistry and Biophysics, 1977
Aryl hydrocarbon hydroxylase (AHH) activity has been demonstrated in the nucleus by a specific histofluorescent technique. The nuclear AHH is present at 15–20% of the activity of the microsomal enzyme. The properties of the nuclear and microsomal AHH have been compared.
E, Bresnick, J B, Vaught, A H, Chuang, T A, Stoming, D, Bockman, H, Mukhtar   +5 more
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Genetic expression of aryl hydrocarbon hydroxylase activity in the mouse

Journal of Cellular Physiology, 1975
Monooxygenases require NADPH and molecular oxygen during the metabolism of numerous endogenous hydrophobic substrates and carcinogenic and toxic exogenous chemicals. The complexity of these membrane-bound multicomponent drug-metabolizing enzyme systems is reviewed.
Nebert, D W, Robinson, J R, Niwa, A, Kumaki, K, Poland, A P   +4 more
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Beryllium Effects on Aryl Hydrocarbon Hydroxylase in Rat Lung

Archives of Environmental Health: An International Journal, 1973
This study was undertaken to determine whether beryllium would interfere with pulmonary mixed function oxidases. Rats were injected intratracheally with 150 μmols/kg of a neutralized solution of beryllium sulfate (BeSO4). The activity of pulmonary aryl hydrocarbon hydroxylase (AHH) was measured one, two, and seven days, and two and four weeks after ...
A, Jacques, H R, Witschi
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