Results 11 to 20 of about 3,554 (178)

Mouse Epidermal Aryl Hydrocarbon Hydroxylase

open access: bronzeJournal of Investigative Dermatology, 1976
Mouse skin contains a NADPH-dependent, aryl hydrocarbon hydroxylase (AHH), which is inducible by polycyclic aromatic hydrocarbons. In general, unsubstituted polycyclic hydrocarbons caused a greater induction of epidermal AHH than substituted one (1,2,3,4-dibenzanthracene greater than 1,2,5,6-dibenzanthracene greater than benz (a)anthracene equal 3 ...
Sara Thompson, Thomas J. Slaga
openalex   +3 more sources

aryl hydrocarbon hydroxylase

open access: gold
Citation: 'aryl hydrocarbon hydroxylase' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.14448 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.

openalex   +2 more sources

Genetic Expression of Aryl Hydrocarbon Hydroxylase Induction

open access: hybridJournal of Biological Chemistry, 1974
Joseph R. Robinson   +2 more
  +4 more sources

Tryptophan metabolite atlas uncovers organ, age, and sex-specific variations. [PDF]

open access: yesFEBS Open Bio
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Perez-Castro L   +8 more
europepmc   +2 more sources

Human Skin Aryl Hydrocarbon Hydroxylase [PDF]

open access: bronzeJournal of Clinical Investigation, 1978
David R. Bickers, Attallah Kappas
openalex   +2 more sources

Chemistry, Applications, and Synthesis Methods of Indole Derivatives: A Comprehensive Review. [PDF]

open access: yesChem Rec
Indole and its derivatives represent a vital class of heterocycles with broad applications in pharmaceuticals, agrochemicals, and materials science. This review explores their applications, biosynthesis, key derivatives such as tryptophan, and presents an overview of both classical and modern synthetic methodologies, with a focus on sustainable ...
Silva Moratório de Moraes R   +10 more
europepmc   +2 more sources

Host–microbiota interaction drives 5‐hydroxyindole‐3‐acetic acid production to promote linear growth in infant mice

open access: yesiMetaOmics, EarlyView.
This study discovered that Lactiplantibacillus plantarum Hi188 promoted linear growth in postweaning mice. Transcriptomic analysis, untargeted metabolomics, and in vitro experiments showed that the elevated levels of 5‐hydroxyindole‐3‐acetic acid (5‐HIAA) activated the hepatic aryl hydrocarbon receptor (AhR) and subsequently promoted insulin‐like ...
Yongmei Yang   +7 more
wiley   +1 more source

Identification and Validation of Biomarkers in Chronic Rhinosinusitis With Nasal Polyps and Study of Their Associated Mechanisms

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Cell senescence (CS) and lipid metabolism (LM) disorders have been reported in chronic rhinosinusitis with nasal polyps (CRSwNP). However, the mechanism is still unclear. Methods Data were obtained from public databases; differential expression analysis and machine learning were performed to identify biomarkers and to understand the
Hui‐Yi Deng   +3 more
wiley   +1 more source

Oxygen‐independent expression of HIF‐1α during the cell cycle in hepatocellular carcinoma cells controls essential metabolic pathways under normoxia

open access: yesThe FEBS Journal, EarlyView.
In Huh7 cells, HIF‐1α is essential as it maintains the expression of proteins involved in glycolysis and steroid/cholesterol biosynthesis both under normoxia and hypoxia. On the other hand, in HeLa cells, these pathways are induced by HIF‐1α only under hypoxia.
Ioanna‐Maria Gkotinakou   +6 more
wiley   +1 more source

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