Results 211 to 220 of about 17,361 (234)

Arylamine N-acetyltransferase (NAT2) genotypes in a Turkish population

Pharmacogenetics, 1997
A group of 303 unrelated Turkish subjects from south-east Anatolia was genotyped for seven NAT2 mutations by polymerase chain reaction-restriction fragment length polymorphism. Genotypes associated with slow acetylation were identified in 57.4% (95%-confidence limits, 51.6%-63.1%).
A S, Aynacioglu, I, Cascorbi, P M, Mrozikiewicz, I, Roots   +3 more
openaire   +2 more sources

Arylamine N‐Acetyltransferase in Erythrocytes of Cystic Fibrosis Patients

Pharmacology & Toxicology, 1996
Abstract:Sulphamethoxazole, a substrate of human arylamine N‐acetyltransferase, is used in the treatment of cystic fibrosis patients, who metabolise the drug rapidly. Increased metabolic clearance of sulphamethoxazole has been suggested to account for this rapid metabolism.
A, Risch, V, Smelt, D, Lane, L, Stanley, W, van der Slot, A, Ward, E, Sim   +6 more
openaire   +2 more sources

Polymorphism in the human arylamine N-acetyltransferase 1 gene 3'-untranslated region determines polyadenylation signal usage.

Biochemical Pharmacology, 2022
C. Choudhury, N. Butcher, R. Minchin
semanticscholar   +1 more source

Arylamine N-acetyltransferase activity in Staphylococcus aureus.

Zhonghua Minguo wei sheng wu ji mian yi xue za zhi = Chinese journal of microbiology and immunology, 1999
N-Acetyltransferase (NAT) activities were determined by incubation of Staphylococcus aureus cytosols with p-aminobenzoic acid (PABA) or 2-aminofluorene (2-AF) followed by high pressure liquid chromatography assays. The NAT activities from S. aureus were found to be 0.67 +/- 0.04 nmol/min/mg protein for the acetylation of 2-AF and 0.46 +/- 0.02 nmol/min/
F C, Chang, J G, Chung, W C, Chang, L T, Wu, G W, Chen, S H, Chang   +5 more
openaire   +1 more source

Arylamine N-acetyltransferase activities in human breast cancer tissues.

Neoplasma, 2001
N-Acetyltransferase activities were determined in tumor (12 malignant and 6 benign) and control (non-cancerous) breast tissues from 18 female patients. The activities of matched 12 malignant tumor and control tissue cytosols showed 6 rapid, 4 intermediate and 2 slow acetylators based on p-aminobenzoic acid (NAT1) and sulfamethazine (NAT2) as substrates.
Geylan, YS, Sak, SD, Güray, Nülüfer Tülün   +2 more
openaire   +2 more sources

Eukaryotic arylamine N-acetyltransferase

Biochemical Pharmacology, 2005
Akane Kawamura, James Graham, Adeel Mushtaq, Stefanos A. Tsiftsoglou, Gregory M. Vath, Patrick E. Hanna, Carston R. Wagner, Edith Sim   +7 more
openaire   +1 more source

Human Arylamine N-Acetyltransferase Genes: Isolation, Chromosomal Localization, and Functional Expression

DNA and Cell Biology, 1990
M. Blum, D. Grant, W. Mcbride, M. Heim, U. Meyer   +4 more
semanticscholar   +1 more source

Fluorescence-based visual analysis and inhibitor screening of Arylamine N-acetyltransferase 2, a key enzyme for tuberculosis

Sensors and Actuators B: Chemical, 2022
Fei Yan, Zhenhao Tian, Yonggang Yang, Xiangge Tian, Xiuyan Han, Lei Feng, Jingnan Cui, Xiaochi Ma   +7 more
semanticscholar   +1 more source

Arylamine N-Acetyltransferases

2018
N. Laurieri, E. Polycarpou, E. Sim
openaire   +1 more source

Arylamine N-acetyltransferase

Biochemical Society Transactions, 1992
E, Sim, D, Hickman, E, Coroneos, S L, Kelly   +3 more
openaire   +2 more sources