Results 101 to 110 of about 7,533 (241)

The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients [PDF]

, 2012
Some unverified reports around the world demonstrated that Purslane has therapeutic effects on some conditions. The aim of this study was to compare the effects of Purslane and Lovastatin therapy in decreasing serum lipids, lipoproteins, and paraoxanase1
Farrokhi, Effat., Gatreh Samani, Keihan., Karimi, Ali., Moradi, Mohammad-Taghi., Rafieian-Kopaei, Mahmoud.   +4 more
core  

Cholesterol transport and beyond: Illuminating the versatile functions of HDL apolipoproteins through structural insights and functional implications

BioFactors, Volume 50, Issue 5, Page 922-956, September/October 2024.
High‐density lipoproteins are versatile lipoprotein nanoparticles that have pleotropic functions in regulating lipid metabolism, innate immunity, and protection of cardiovascular system. They comprise of several proteins among which 15 apolipoproteins are the major proteins, with diverse functions.
Aishwarya Sudam Bhale, Olivier Meilhac, Christian Lefebvre d'Hellencourt, Mookambeswaran A. Vijayalakshmi, Krishnan Venkataraman   +4 more
wiley   +1 more source

Effects of Vitamin C on Paraoxonase1 Arylesterase Activity in Rats Exposed to Arsenic

, 2017
Background: Arsenic as an environmental toxicant is able to induced oxidative stress. The present study aimed to evaluate of vitamin C supplementation on the paraoxonase1 (PON1) arylesterase activity (responsible for hydrolysing lipid-peroxides) in rat ...
Felor Zargari, Hamid Tabaghchi Saeedy
semanticscholar   +1 more source

مطالعه فنوتيپ‌ها و فعاليت آنزيم پارااکسوناز در بيماران مبتلا به گرفتگی عروق کرونر [PDF]

, 2005
آنزيم پارااکسوناز می‌تواند استرهای آلی فسفات‌دار را هيدروليز نمايد. مهم‌ترين سوبسترای اين آنزيم در مطالعات آزمايشگاهی پارااکسون است. در سرم انسان اين آنزيم همراه با HDL در خون جريان دارد.
حسينی گوهری, لادن, زواره‌ای, عباس, فيروزرای, محسن, نفيسی, نرگس   +3 more
core  

Effects of Metabolic Disruption on Lipid Metabolism and Yolk Retention in Zebrafish Embryos

Environmental Toxicology and Chemistry, Volume 43, Issue 8, Page 1880-1893, August 2024.
Abstract A subgroup of endocrine‐disrupting chemicals have the ability to disrupt metabolism. These metabolism‐disrupting chemicals (MDCs) can end up in aquatic environments and lead to adverse outcomes in fish. Although molecular and physiological effects of MDCs have been studied in adult fish, few studies have investigated the consequences of ...
Rik van den Boom, Lucia Vergauwen, Dries Knapen   +2 more
wiley   +1 more source

A long and winding road: defining the biological role and clinical importance of paraoxonases [PDF]

, 2017
Paraoxonase-1 (PON1) is an enzyme belonging to a three-member gene family, each of which is highly conserved in mammalian evolution. Whilst there is consensus that the paraoxonase family members have a general protective influence, their precise ...
James, Richard W.
core  

High-Density Lipoprotein Antioxidant Responses to High-Intensity Interval and Steady-State Moderate-Intensity Exercise [PDF]

, 2015
High-intensity interval exercise (HIIE) may impart health benefits beyond what is acquired through moderate-intensity steady state exercise (SSE). Paraoxonase 1 (PON1), an antioxidant associated with high-density lipoprotein (HDL), may be altered with ...
Bane, Annie A, Forsse, Jeffrey S, Grandjean, Peter W, Kyle, Taylor, Morales Marroquín, Flor Elisa, Papadakis, Zacharias, Qian, Li   +6 more
core   +2 more sources

Relationship of Serum Paraoxonase Enzyme Activity and Thermal Burn Injury

Eurasian Journal of Medicine, 2012
Objective: This study investigated changes in serum oxidative stress parameters in burn cases compared to healthy controls. Materials and Methods: This study was performed in 41 burn patients with mild to severe thermal burn injuries and 38 healthy ...
Serap Yildirim, Songul Doganay, Abdulkadir Yildirim, Osman Enver Aydin, Akar Karakoc, Esra Laloglu   +5 more
doaj  

The number of PON1 mutant alleles, but not PON1 phenotype, is associated with Gensini score of coronary damage

Romanian Journal of Laboratory Medicine, 2013
Obiective. Scopul acestui studiu a fost de a examina efectele polimorfismelor (SNPs) genei PON1 la nivelul regiunii promotor (-909 şi -832) şi a primului exon (+575, 20352A>G, rezultând substituirea Q192R) asupra activităţilor paraoxonazei-1 (PON1) într ...
Ilea Irina, Lupan Iulia, Leucuta Daniel Corneliu, Duncea Caius Romulus, Dronca Maria   +4 more
doaj   +1 more source

Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities

Journal of Lipid Research, 2005
The paraoxonase (PON) gene family in humans has three members, PON1, PON2, and PON3. Their physiological role(s) and natural substrates are uncertain. We developed a baculovirus-mediated expression system, suitable for all three human PONs, and optimized
Dragomir I. Draganov, John F. Teiber, Audrey Speelman, Yoichi Osawa, Roger Sunahara, Bert N. La Du   +5 more
doaj   +1 more source