Results 11 to 20 of about 628 (144)

Proteoglycan desulfation: a critical step in oncogenesis?

open access: yesFrontiers in Bioscience-Landmark, 2020
Proteoglycans are essential constituents of tissue- and organ microenvironments, modulating both the structural scaffolds that surround cells as well as signaling cues that determine cellular phenotype.
Vishal Singh, Ramray Bhat
doaj   +1 more source

Lysosomal arylsulfatase deficiencies in humans: Chromosome assignments for arylsulfatase A and B [PDF]

open access: yesProceedings of the National Academy of Sciences, 1979
Genetics of human lysosomal arylsulfatases A and B (aryl-sulfate sulfohydrolase, EC 3.1.6.1), associated with childhood disease, has been studied with human-rodent somatic cell hybrids. Deficiency of arylsulfatase A (ARS A ) in humans results in a progressive neurodegenerative disease, metachromatic leukodystrophy ...
C, DeLuca, J A, Brown, T B, Shows
openaire   +2 more sources

Lysosomal hydrolases in neuronal, astroglial, and olidodendroglial enriched fractions of rabbit and beef brain.

open access: yesJournal of Lipid Research, 1979
Arylsulfatases A, B, and C, beta-galactosidase, and acid phosphatase were assayed in neuronal, astroglial, and oligodendroglial fractions isolated from adult rabbit and beef brains.
L Freysz   +3 more
doaj   +1 more source

Radioiodination of Aryl-Alkyl Cyclic Sulfates

open access: yesMolecules, 2012
Among the currently available positron emitters suitable for Positron Emission Tomography (PET), 124I has the longest physical half-life (4.2 days).
Mikhail I. Papisov, Chandra Mushti
doaj   +1 more source

Comparative Genomic Analysis of Clinical and Environmental Vibrio Vulnificus Isolates Revealed Biotype 3 Evolutionary Relationships

open access: yesFrontiers in Microbiology, 2015
In 1996 a common-source outbreak of severe soft tissue and bloodstream infections erupted among Israeli fish farmers and fish consumers due to changes in fish marketing policies. The causative pathogen was a new strain of Vibrio vulnificus, named biotype
Yael eKotton   +5 more
doaj   +1 more source

Localization of arylsulfatase in Pseudomonas C12B [PDF]

open access: yesApplied and Environmental Microbiology, 1977
Arylsulfatase was released almost completely from intact cells of Pseudomonas C12B after osmotic shock or after treatment with lysozyme. These results suggest that the enzyme is cell wall associated in this soil isolate.
J W, Fitzgerald, J R, George
openaire   +2 more sources

Chemical Metabolomics: Chemical Biology Tools for Advanced Metabolism Investigations

open access: yesAngewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The human metabolism has been investigated for several millennia. The metabolome is known for a high complexity due to a large number of different metabolites that are present at different concentrations. Metabolomics has been developed as a field to investigate the entire human metabolome and to elucidate disease development mechanisms.
Alejandro Torregrosa‐Chinillach   +4 more
wiley   +2 more sources

Endogenous melatonin partial metabolic clearance as a potential endogenous marker of CYP1A2 activity

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Cytochrome P450 1A2 (CYP1A2) exhibits substantial interindividual variability, necessitating appropriate phenotyping strategies for personalized pharmacotherapy. This study evaluated endogenous melatonin partial metabolic clearance (CLm(MEL)), calculated from urinary 6‐hydroxymelatonin (6‐O‐MEL) excretion and plasma melatonin (MEL) exposure, as a ...
Akitomo Yokokawa   +5 more
wiley   +1 more source

Assessment of Gold‐Mediated Male Reproductive Dysfunction in Male WISTAR Rats Through Sperm Analysis and Testosterone Measurement

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Gold has been used for centuries in both ornamental and medicinal contexts. More recently, gold compounds, containing ions or nanoparticles, have attracted attention for their anti‐inflammatory, anticancer, and diagnostic applications. Therefore, concerns about systemic toxicity and biodistribution have prompted investigations into the ...
Samira Maghraoui   +2 more
wiley   +1 more source

Assessing Soil and Management Quality Indexes in A Rural Watershed Under Long‐Term No‐Tillage in Southern Brazil

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Soil quality assessment is essential to detect management failures and prevent land degradation in agricultural systems. No‐tillage system (NTS) is a conservation management widely adopted in Brazil, but its effectiveness is compromised when adherence to the core principles of crop rotation and ground cover is not complete, and basic ...
Edson Lucas Camilo   +5 more
wiley   +1 more source

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