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PA-Kontaminationen in Arzneipflanzen: Vorkommen, Grenzwerte und Maßnahmen

Journal für Kulturpflanzen, 2020
Seit mehreren Jahren wird eine mögliche Kontamination von Arzneipflanzen mit pyrrolizidinalkaloid-haltigen Beikräutern diskutiert. Die Erkenntnisse über ein solches Risiko hat die Anbauer und Lieferanten pflanzlicher Drogen und die Hersteller von ...
Barbara Steinhoff
doaj +1 more source

KOH 5% solution versus diclofenac 3% for the treatment of actinic keratosis – Results from a three‐armed RCT

Journal of the European Academy of Dermatology and Venereology, EarlyView.
In this RCT, KOH 5% demonstrated superior clinical success to diclofenac 3% and placebo at the end of treatment in patients with mild‐to‐moderate actinic keratosis and comparable long‐term efficacy to diclofenac. Its fast onset of efficacy and favourable tolerability make KOH a valuable treatment option in early‐stage actinic keratosis treatment ...
U. Reinhold +18 more
wiley +1 more source

Die Festbetragsregelung im AMNOG-Markt – ein Blick aus der Praxis

Monitor Versorgungsforschung
Dieser Beitrag untersucht die praktische Umsetzung der Schnittstelle zwischen den Preisregulierungsinstrumenten AMNOG und Festbetrag im deutschen Arzneimittelmarkt von 2011 bis Juli 2024. Dabei werden drei typische Fallkonstellationen der Verknüpfung der
Susann Lukat, Dr. Ulrike Götting
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Status Epilepticus After Electrocution Injury in a Dog

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Objective To describe a case of status epilepticus secondary to electrocution injury associated with an electric fence. Case Summary A 1.5‐year‐old male Kangal Shepherd Dog mix was presented to the emergency service after being entangled in an agricultural electric fence for 1–2 h. On presentation, the dog was recumbent, was unable to stand or
Julia Ortlieb +5 more
wiley +1 more source

Intra-Seasonal Initiation of the SQ-Standardised Grass Allergy Immunotherapy Tablet Routinely Applied by Allergy Specialists and General Practitioners with Experience in Treatment of Allergy: A Non-Interventional Observational Study

Pulmonary Therapy, 2018
Introduction Intra-seasonal start of treatment with the SQ® grass sublingual immunotherapy(SLIT) tablet (GRAZAX®, ALK, Denmark) has been previously demonstrated to be well-tolerated. The objective of our study was to investigate the tolerability of intra-
Jan-Alexander Schwab +3 more
doaj +1 more source

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner +6 more
wiley +1 more source

Early intervention with azelastine nasal spray may reduce viral load in SARS-CoV-2 infected patients

Scientific Reports, 2023
With the changing epidemiology of COVID-19 and its impact on our daily lives, there is still an unmet need of COVID-19 therapies treating early infections to prevent progression.
Jens Peter Klussmann +26 more
doaj +1 more source

Regulatorische Handhabung der selektiven Erstattung von Arzneimitteln in den ausgewählten Ländern England, Niederlande, Frankreich und Schweden [PDF]

, 2015
[Einleitung] Im Rahmen des AMNOG wurde die Preisbildung für patentgeschützte Arzneimittel und damit die Erstattung durch die GKV neu geregelt. Seit 2011 wird in einer Verhandlung festgelegt, wie viel die Krankenkassen ab dem 13.
Bauer, Cosima +5 more
core

Allergic Rhinitis and Its Impact on Asthma (ARIA)‐EAACI Guidelines—2024–2025 Revision: Part I—Guidelines on Intranasal Treatments

Allergy, Volume 81, Issue 4, Page 954-976, April 2026.
ABSTRACT Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI‐endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024 ...
Bernardo Sousa‐Pinto +252 more
wiley +1 more source

Efficacy of two dosing schemes of a liquid containing ivy leaves dry extract EA 575 versus placebo in the treatment of acute bronchitis in adults

ERJ Open Research, 2019
Introduction The results of a clinical trial published in 2016 showed the efficacy of ivy leaves dry extract EA 575 versus placebo in the treatment of patients suffering from acute cough.
Axel Schaefer +4 more
doaj +1 more source

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