Results 41 to 50 of about 9,502 (222)

Vascular Dynamics During Respiratory Arousal From Sleep Assessed by Oximeter‐Based Vascular Stiffness Measures

Journal of Sleep Research, EarlyView.
ABSTRACT Cortical arousals significantly impact obstructive sleep apnoea (OSA) pathophysiology and cardiovascular consequences, often mediated by sympathetic activation. While pulse oximetry (PPG) provides an accessible reflection of autonomic responses such as changes in pulse rate (PR) and pulse wave amplitude (PWA), the dynamic influence on other ...
Christian Strassberger, Ding Zou, Jan Hedner, Ludger Grote   +3 more
wiley   +1 more source

PA-Kontaminationen in Arzneipflanzen: Vorkommen, Grenzwerte und Maßnahmen

Journal für Kulturpflanzen, 2020
Seit mehreren Jahren wird eine mögliche Kontamination von Arzneipflanzen mit pyrrolizidinalkaloid-haltigen Beikräutern diskutiert. Die Erkenntnisse über ein solches Risiko hat die Anbauer und Lieferanten pflanzlicher Drogen und die Hersteller von ...
Barbara Steinhoff
doaj   +1 more source

Evaluation of a Partial Ban on Rx‐Rebates in Germany

Health Economics, Volume 35, Issue 8, Page 1247-1274, August 2026.
ABSTRACT We investigate patients' price sensitivity for prescription (Rx) drugs with regards to patronizing online or brick‐and‐mortar pharmacies. In doing so, we exploit a policy change in Germany that prohibited online pharmacies from granting rebates to one part of the population, the members of the statutory health insurance scheme.
Maximilian M. Gail, Georg Götz, Daniel Herold, Jan T. Schäfer   +3 more
wiley   +1 more source

Intra-Seasonal Initiation of the SQ-Standardised Grass Allergy Immunotherapy Tablet Routinely Applied by Allergy Specialists and General Practitioners with Experience in Treatment of Allergy: A Non-Interventional Observational Study

Pulmonary Therapy, 2018
Introduction Intra-seasonal start of treatment with the SQ® grass sublingual immunotherapy(SLIT) tablet (GRAZAX®, ALK, Denmark) has been previously demonstrated to be well-tolerated. The objective of our study was to investigate the tolerability of intra-
Jan-Alexander Schwab, Hendrik Wolf, Jörg Schnitker, Eike Wüstenberg   +3 more
doaj   +1 more source

Prophylactic Olanzapine Versus Placebo in Comatose Survivors of Out‐of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest (DANOHCA) Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 7, August 2026.
ABSTRACT Background Delirium is a frequent complication in comatose Out‐of‐Hospital Cardiac Arrest (OHCA) survivors requiring postresuscitation intensive care and is associated with higher mortality and longer hospitalization. Despite this, there is no established pharmacologic strategy for delirium prevention in OHCA survivors.
Benedikte Liebetrau, Anders M. Grejs, Martin A. S. Meyer, Lars P. K. Andersen, Sören Möller, Simon Mølstrøm, Jacob E. Møller, Henrik Schmidt, Steffen Christensen, Jesper Kjærgaard, Christian Hassager, Bodil S. Rasmussen, Jo B. Andreasen   +12 more
wiley   +1 more source

Neues Symbol für Arzneimittel unter zusätzlicher Überwachung

, 2013
In der Packungsbeilage bestimmter Arzneimittel auf dem EU-Markt wird in Kürze ein auf der Spitze stehendes schwarzes Dreieck zu sehen sein. Die Europäische Kommission hat am 7. März 2013 einen entsprechenden Rechtsakt angenommen.
Weisser, Karin
core   +2 more sources

Effects of Transcutaneous Electrical Nerve Stimulation, Electrical Muscle Stimulation, Exercise and Heat on Back Pain—A Randomized Controlled Clinical Exploratory Trial

European Journal of Pain, Volume 30, Issue 6, July 2026.
ABSTRACT Background This randomized controlled study compared different forms of therapy for chronic back pain. Methods Seventy‐nine patients with chronic back pain with a duration of symptoms of more than 6 months were included in the study and randomly assigned to one of four therapy groups (a) sports therapy with a focus on strength training (SG ...
Thorsten Schmidt, Sonja Kossiski, Hanna Kornprobst, Laura von Levern, Dominik M. Schulte, Manon Sendel, Ralf Baron, Janne Gierthmühlen   +7 more
wiley   +1 more source

Efficacy of two dosing schemes of a liquid containing ivy leaves dry extract EA 575 versus placebo in the treatment of acute bronchitis in adults

ERJ Open Research, 2019
Introduction The results of a clinical trial published in 2016 showed the efficacy of ivy leaves dry extract EA 575 versus placebo in the treatment of patients suffering from acute cough.
Axel Schaefer, Fanny Ludwig, Bruno M. Giannetti, Michael Bulitta, Anja Wacker   +4 more
doaj   +1 more source

Real‐world progression‐free survival and overall survival in patients with HR+/HER2− advanced breast cancer treated in first‐line with ribociclib, endocrine monotherapy or chemotherapy: Results from the observational RIBANNA study

International Journal of Cancer, Volume 159, Issue 1, Page 210-223, 1 July 2026.
What's New? The CDK4/6 inhibitor ribociclib in combination with an endocrine‐based therapy has demonstrated significant progression‐free and overall survival benefits in patients with advanced/metastatic HR+/HER2‐ breast cancer in the pivotal MONALEESA trials.
Peter A. Fasching, Cosima Brucker, Thomas Decker, Anne Engel, Thomas Göhler, Christian Jackisch, Jan Janssen, Andreas Köhler, Kerstin Lüdtke‐Heckenkamp, Diana Lüftner, Frederik Marmé, Marion van Mackelenbergh, Beate Rautenberg, Marcus Schmidt, Rudolf Weide, Pauline Wimberger, Elena Kisseleff, Christina Pfister, Claudia Quiering, Christian Roos, Achim Wöckel   +20 more
wiley   +1 more source

A deep learning‐enabled toolkit for the 3D segmentation of ventricular cardiomyocytes

The Journal of Physiology, Volume 604, Issue 13, Page 5561-5584, 1 July 2026.
Abstract figure legend 3D cardiomyocyte segmentation enables comprehensive analyses of myocardial microstructure in health and disease; however, it is technically demanding. We present an open‐source toolkit for this task, which reduces challenges associated with sample preparation, image restoration, segmentation and proofreading.
Joachim Greiner, Fabio Frangiamore, Frédéric Sonak, Josef Madl, Thomas Seidel, Peter Kohl, Eva A. Rog‐Zielinska   +6 more
wiley   +1 more source