Results 51 to 60 of about 145,273 (229)
Integrating polygenic and methylation risk scores for pleural mesothelioma risk stratification
International Journal of Cancer, EarlyView.What's New? Asbestos exposure is a major risk factor for pleural mesothelioma (PM). Most asbestos‐exposed individuals do not develop PM, suggesting that it arises from a complex interplay between environmental and genetic factors. This study examined the utility of polygenic risk scores (PRS) and methylation risk scores (MRS) in incorporating genetic ...
Khadija Sana Hafeez +26 more
wiley +1 more source
Toxics, 2023 Malignant mesothelioma and asbestos-related lung cancer are typically associated with a poor prognosis. However, it has been observed that some patients with these cancers survive significantly longer than the average survival period.
Min-Sung Kang +3 more
doaj +1 more source
International Journal of Cancer, EarlyView.What's New? Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic precursor to multiple myeloma, sharing substantial genetic features with overt malignancy. Given evidence implicating autophagy in myeloma risk, this study examined whether genetic variations in autophagy‐related genes influence MGUS susceptibility.
José Manuel Sánchez‐Maldonado +54 more
wiley +1 more source
The Genomic Evolution of Early‐Stage Non‐Small Cell Lung Cancer
Medicine Advances, EarlyView.This study provides a comprehensive overview of the genomic landscape of early‐stage non‐small cell lung cancer, identifying the 4q12 deletion as a potential exclusive biomarker for the “oncogenic switch” from pre‐invasive to invasive lesions. It delineates that while EGFR and TP53 mutations act as early truncal drivers, the progressive increase in ...
Huatao Tang, Yang Zhang, Haiquan Chen
wiley +1 more source
Scientific DataTime-critical transcriptional events in the immune microenvironment are important for response to immune checkpoint blockade (ICB), yet these events are difficult to characterise and remain incompletely understood.
Wee Loong Chin +13 more
doaj +1 more source
The Hidden Costs of Coffee Production in the Eastern African Value Chains
Sustainable Development, EarlyView.ABSTRACT There is increasing recognition that significant hidden costs associated with agrifood systems are not reflected in market prices. Coffee is among the three most traded agricultural commodities in the world and supports the livelihoods of more than 30 million smallholder households.
Annet Adong +3 more
wiley +1 more source
The Evolution of Asbestos Bankruptcy Trust Distribution Plans [PDF]
, 2006 The evolution of asbestos litigation from the early 1970s to the present has become the source of much analysis. One commentator divides this history into several phases: the heroic phase, bureaucratic floundering, adaptation and maturity, search for ...
McGovern, Francis
core +1 more source
The Role of Companion Animals as 'Sentinels' From the One Health Perspective. [PDF]
Vet Med SciOne Health emphasizes the interconnection of human, animal and environmental health. As emotional extensions of humans, companion dogs and cats can serve as sentinels, detecting hazards that can help protect human health from the One Health perspective. When symptoms appear in pets, owners should notice the changes that may pose risks to both human and
Kang S, Chen Y, Liu M.
europepmc +2 more sources
Consumed by Abdominal Distention
Arthritis Care &Research, EarlyView.
Abimbola Fadairo‐Azinge +3 more
wiley +1 more source
Small, EarlyView.ABSTRACT Urban heat islands have become a global issue, as they severely impact several key factors, including elevated energy consumption, increased air pollution and greenhouse gas emissions, compromised human health and comfort, and reduced water quality.
G.P. Darshan +5 more
wiley +1 more source