Results 61 to 70 of about 54,182 (246)

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Hidden Targets in Cancer Immunotherapy: The Potential of “Dark Matter” Neoantigens

Vaccines
The development of cancer immunotherapies has transformed cancer treatment paradigms, yet durable and tumour-specific responses remain elusive for many patients.
Francois Xavier Rwandamuriye, Alec J. Redwood, Jenette Creaney, Bruce W. S. Robinson   +3 more
doaj   +1 more source

Covering Up for Coworkers: A Scale Development and Empirical Examination of Relational Cover‐Up Behavior

Journal of Organizational Behavior, EarlyView.
ABSTRACT Why do employees conceal their coworkers' unethical behavior and who is most likely to do so? To address these questions, we begin by developing and validating a psychometrically robust measure of relational cover‐up behavior (Study 1). Using a two‐wave study (N = 475), we then test the argument that employees may experience an identity threat
Jenny H. Wang, Annika Hillebrandt, Laurie J. Barclay   +2 more
wiley   +1 more source

Determinants of the Perception of Asbestos

Safety & Fire Technology, 2019
Aim: The purpose of the article is to provide general information about the properties, application, legal aspects and methods of asbestos disposal. In addition, studies on the harmfulness of asbestos impact on the incidence of asbestos-related diseases ...
Dorota Szułczyńska
doaj   +1 more source

The Hidden Costs of Coffee Production in the Eastern African Value Chains

Sustainable Development, EarlyView.
ABSTRACT There is increasing recognition that significant hidden costs associated with agrifood systems are not reflected in market prices. Coffee is among the three most traded agricultural commodities in the world and supports the livelihoods of more than 30 million smallholder households.
Annet Adong, Lukas Kornher, Bezawit Beyene Chichaibelu, Aslihan Arslan   +3 more
wiley   +1 more source

Welcome to Cassiar Country: [PDF]

, 1970
The Cassiar story -- Asbestos: the wonder mineral -- Mining, milling and marketing -- Community life -- Asbestos and the working ...

core  

Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner

BMC Cancer
Background Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved response rates and ...
Caitlin M. Tilsed, M. Lizeth Orozco Morales, Rachael M. Zemek, Brianna A. Gordon, Matthew J. Piggott, Anna K. Nowak, Scott A. Fisher, Richard A. Lake, W. Joost Lesterhuis   +8 more
doaj   +1 more source

Live-cell imaging of macrophage phagocytosis of asbestos fibers under fluorescence microscopy

Genes and Environment, 2019
Background Frustrated phagocytosis occurs when an asbestos fiber > 10 μm in length is engulfed imperfectly by a macrophage, and it is believed to be associated with chromosomal instability.
Takenori Ishida, Nobutoshi Fujihara, Tomoki Nishimura, Hisakage Funabashi, Ryuichi Hirota, Takeshi Ikeda, Akio Kuroda   +6 more
doaj   +1 more source

Strategies to Advance the Energy Efficiency, Water Efficiency, and Indoor Environmental Quality in New Zealand's Sustainable Building Designs and Practices

Sustainable Development, EarlyView.
ABSTRACT Sustainable Building Designs and Practices (SBDPs) are increasingly important for reducing environmental impacts, conserving resources, and improving occupant well‐being. This study examines New Zealand building professionals' perceptions of the integration and performance of energy efficiency (EE), water efficiency (WE), and Indoor ...
Tharaya Poorisat, Itohan Esther Aigwi, Dat Tien Doan, Ali GhaffarianHoseini   +3 more
wiley   +1 more source

Neoantigen load as a predictor of relapse in early-stage NSCLC: features that agonise and antagonise prognosis

Cancer Immunology, Immunotherapy
Background Neoantigen-specific immune responses may help prevent cancer recurrence. We evaluated whether neoantigen load and/or properties could predict survival in early-stage non-small cell lung cancer (NSCLC). Methods Whole-exome sequencing (WES) data
Linda Ye, Ian Dick, Bruce W. Robinson, Jenette Creaney, Alec Redwood   +4 more
doaj   +1 more source