Results 51 to 60 of about 27,852 (210)
Hidden Targets in Cancer Immunotherapy: The Potential of “Dark Matter” Neoantigens
VaccinesThe development of cancer immunotherapies has transformed cancer treatment paradigms, yet durable and tumour-specific responses remain elusive for many patients.
Francois Xavier Rwandamuriye +3 more
doaj +1 more source
Determinants of the Perception of Asbestos
Safety & Fire Technology, 2019 Aim: The purpose of the article is to provide general information about the properties, application, legal aspects and methods of asbestos disposal. In addition, studies on the harmfulness of asbestos impact on the incidence of asbestos-related diseases ...
Dorota Szułczyńska
doaj +1 more source
Monitoring of historical structural materials with computed tomography
Structural Concrete, EarlyView.Abstract Computed tomography (CT) is an excellent tool to solve certain engineering problems connected to material science (such as sulfate swelling, internal degradation due to freezing, and alkali silicate swelling) and to understand specific processes (frost peeling, acid action).
Kristóf Csorba +5 more
wiley +1 more source
Tretinoin improves the anti-cancer response to cyclophosphamide, in a model-selective manner
BMC CancerBackground Chemotherapy is included in treatment regimens for many solid cancers, but when administered as a single agent it is rarely curative. The addition of immune checkpoint therapy to standard chemotherapy regimens has improved response rates and ...
Caitlin M. Tilsed +8 more
doaj +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Mold growth in damp indoor environments is a widespread problem associated with respiratory health effects, though causal mechanisms remain incompletely understood. We established a human cell‐based in vitro test system using bronchial epithelial cells (NuLi‐1) and macrophages (THP‐1) to assess inhalation toxicity and immunomodulatory effects ...
Anja Wolff +8 more
wiley +1 more source
Cancer Immunology, ImmunotherapyBackground Neoantigen-specific immune responses may help prevent cancer recurrence. We evaluated whether neoantigen load and/or properties could predict survival in early-stage non-small cell lung cancer (NSCLC). Methods Whole-exome sequencing (WES) data
Linda Ye +4 more
doaj +1 more source
The Effect of Grinding on Tremolite Asbestos and Anthophyllite Asbestos [PDF]
Minerals, 2018 The six commercial asbestos minerals (chrysotile, fibrous actinolite, crocidolite, amosite, fibrous tremolite, and fibrous anthophyllite) are classified by the IARC as carcinogenic to humans. There are currently several lines of research dealing with the inertisation of asbestos minerals among which the dry grinding process has received considerable ...
Andrea Bloise +2 more
openaire +2 more sources
High Voltage, EarlyView.ABSTRACT The problem of gas–solid interface charge accumulation is an important reason for distorting the surface electric field and then inducing surface discharge. The temperature gradient distribution formed on the spacer during the operation of a gas‐insulated transmission line (GIL) will aggravate the surface charge accumulation, further ...
Jianyi Xue +6 more
wiley +1 more source
Live-cell imaging of macrophage phagocytosis of asbestos fibers under fluorescence microscopy
Genes and Environment, 2019 Background Frustrated phagocytosis occurs when an asbestos fiber > 10 μm in length is engulfed imperfectly by a macrophage, and it is believed to be associated with chromosomal instability.
Takenori Ishida +6 more
doaj +1 more source
Firearm Safety in a Country of Arms
The Milbank Quarterly, EarlyView.Policy Points Firearm safety policy in the United States cannot succeed through legislation alone; effective interventions must also address the social, economic, and infrastructural conditions that shape perceptions of safety. Evidence suggests that place‐based investments can reduce violence and firearm deaths while strengthening social cohesion and ...
JONATHAN M. METZL
wiley +1 more source