Background Live-attenuated vaccines (LAVs) are typically contraindicated for immunocompromised patients and pregnant women, although the potential benefits of vaccination with LAV in these populations should not be overlooked.
Giorgia Tiozzo +6 more
doaj +1 more source
Accelerating Stochastic Composition Optimization
Consider the stochastic composition optimization problem where the objective is a composition of two expected-value functions. We propose a new stochastic first-order method, namely the accelerated stochastic compositional proximal gradient (ASC-PG ...
Fang, Ethan X., Liu, Ji, Wang, Mengdi
core
Data Reduction and Analysis of Photometric Data for 48 Evolved Stars from the All Sky Automated Survey and Valparaiso University Observatory [PDF]
We are carrying out research to determine the pulsation period of a specific stage in evolved, low-mass stars’ life cycles called Proto-Planetary Nebulae.
Bremer, Matthew T
core +1 more source
Periodontitis Induces B Cell‐Macrophage Crosstalk to Exacerbate Glucose Dysregulation in Obesity
In obesity, periodontitis exacerbates hyperglycemia and exhibits a liver‐centric preference for glucose regulation. This occurs through a periodontitis‐driven circuit between pathogenic B cells and hepatic macrophages. Their reciprocal expansion, orchestrated by the NLRP3/IL‐18 signaling pathway, amplifies metabolic inflammation and disrupts glucose ...
Wen‐Zhen Lin +19 more
wiley +1 more source
Portrayal of Life Stages on Swedish Municipal Media: A Life Course Perspective
Media portrayal of older adults is an expression of social realities and expectations, and the image of ageing has significant implications for intergenerational relations.
Wenqian Xu
doaj +1 more source
Macrophage‐derived TRIM21 drives the progression of AP via ubiquitin‐proteasome‐mediated degradation of PHB2, leading to impaired PHB2‐mediated mitophagy. Therefore, accumulation of cytosolic mtDNA hyperactivates the cGAS‐STING signaling axis, thereby amplifying inflammatory cascades.
Yansong Xu +7 more
wiley +1 more source
Superconductivity in the pressurized nickelate La3Ni2O7 in the vicinity of a BEC–BCS crossover
Ever since the discovery of high-temperature superconductivity in cuprates, gaining microscopic insights into the nature of pairing in strongly correlated systems has remained one of the greatest challenges in modern condensed matter physics.
Henning Schlömer +3 more
doaj +1 more source
Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das +13 more
wiley +1 more source
HUMAN ADIPOSE-DERIVED STEM CELLS ATTENUATE CIGARETTE SMOKE INDUCED BONE MARROW HYPOPLASIA VIA SECRETION OF ANTI-INFLAMMATORY CYTOKINE TSG-6 [PDF]
poster abstractIntroduction We have previously observed bone marrow (BM) hypo-plasia in a murine model of chronic smoking, which was ameliorated by mu-rine adipose-derived stromal cells (ASC). This study was designed to test the hypothesis that ASC exert
Broxmeyer, Hal E. +7 more
core
Adhesion‐Related Macrophages Regulate Metabolic Homeostasis Through CAV‐1 Dependency
Adipose tissue harbors a distinct macrophage subpopulation, termed adhesion‐related macrophages (ARMs), which stably adhere to adipocytes. In obesity, ARMs represent the major expanding macrophage subset. They acquire material from adipocytes and rely on Caveolin‐1 for sustained lipid handling.
Wanyu Hu +23 more
wiley +1 more source

