Results 71 to 80 of about 263,599 (283)

Start, Stop, Rewind, Repeat—Cyclic Exposure of Adipose Stromal Cells‐derived Cartilage Organoids to Chondrogenic and Proliferative Cues to Achieve Scaled‐up and Customizable Bone Formation by Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
This study exploits the plasticity of ASCs‐derived cartilage organoids which generate a perichondrial layer of MSCs when exposed to cyclic chondrogenic/proliferative cues. Using these organoids as building blocks, we develop (i) Phalange Shaped Tissue Engineered Cartilage (Pa‐TECs), recapitulating endochondral ossification suitable for the treatment of
Pablo Pfister, Emilien Lhospice, Andrés García‐García, Robert Paillaud, Sebastian Jung, Romain Schaller, Elisabeth A. Kappos, Claude Jaquiéry, Tarek Ismail, Dirk J. Schaefer, Michael de Wild, Ivan Martin, Alexandre Kaempfen, Arnaud Scherberich, Adrien Moya   +14 more
wiley   +1 more source

Software correlator for Radioastron mission

, 2017
In this paper we discuss the characteristics and operation of Astro Space Center (ASC) software FX correlator that is an important component of space-ground interferometer for Radioastron project. This project performs joint observations of compact radio
Andrianov, A. S., Girin, I. A., Kostenko, V. I., Likhachev, S. F., Rudnitskiy, A. G., Zharov, V. E.   +5 more
core   +1 more source

Autistic traits affect interpersonal motor coordination by modulating strategic use of role-based behavior [PDF]

, 2017
Background: Despite the fact that deficits in social communication and interaction are at the core of Autism Spectrum Conditions (ASC), no study has yet tested individuals on a continuum from neurotypical development to autism in an on-line, cooperative,
Aglioti, Salvatore Maria, Candidi, Matteo, Curioni, Arianna, Minio-Paluello, Ilaria, Sacheli, Lucia Maria   +4 more
core   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Caspase-1 engagement and TLR-induced c-FLIP expression suppress ASC/caspase-8-dependent apoptosis by inflammasome sensors NLRP1b and NLRC4 [PDF]

, 2017
The caspase activation and recruitment domain (CARD)-based inflammasome sensors NLRP1b and NLRC4 induce caspase-1-dependent pyroptosis independent of the inflammasome adaptor ASC.
D'Hont, Jinke, Demon, Dieter, Gonçalves, Amanda, Hochepied, Tino, Kanneganti, Thirumala-Devi, Krautwald, Stefan, Lamkanfi, Mohamed, Matusiak, Magdalena, Moraes de Vasconcelos, Nathalia, Van Gorp, Hanne, Van Hauwermeiren, Filip, Van Opdenbosch, Nina, Vande Walle, Lieselotte, Verdonckt, Maarten, Viana Saavedra, Pedro Henrique   +14 more
core   +2 more sources

Functional Metal Complexes for Solar–Light‐Driven Energy Conversion

Advanced Materials, EarlyView.
This review provides an exhaustive summary of the recent advancements of functional metal complexes in solar‐to‐electrical, ‐chemical, and ‐thermal energy conversion, comprising material categories, design strategies, underlying principles of operation, and identified improvement of performances.
Yanyan Qin, Dou Luo, Miao Zhang, Wai‐Yeung Wong   +3 more
wiley   +1 more source

Three particles in an external trap: Nature of the complete J=0 spectrum [PDF]

, 2002
Three bosonic, spin-polarized atoms in a spherical oscillator potential constitutes the simplest nontrivial Bose-Einstein condensate (BEC). The present paper develops the tools needed to understand the nature of the complete J=0 energy spectrum for this ...
A. Fabrocini, B. D. Esry, B. D. Esry, B. D. Esry, B. D. Esry, C. D. Lin, Chris H. Greene, D. Blume, D. Blume, D. Blume, D. Blume, E. A. Donley, E. Braaten, E. Braaten, E. H. Lieb, E. Nielsen, E. Nielsen, E. P. Gross, E. P. Gross, E. Timmermans, E. Timmermans, F. A. van Abeelen, F. Dalfovo, H. Saito, H. T. C. Stoof, H. W. van der Hart, J. J. Hope, J. Javanainen, J. L. Bohn, J. Macek, K. Góral, L. P. Pitaevskii, M. Greiner, M. Holland, M. Holland, M. J. Davis, M. Mackie, O. Sørensen, P. D. Drummond, P. F. Bedaque, R. A. Duine, R. C. Whitten, R. J. Dodd, S. A. Morgan, S. L. Cornish, V. A. Yurovsky, Y. E. Kim, Y. E. Kim, Y. Kagan, Y. Zhou   +49 more
core   +2 more sources

High Stability of Diketopyrrolopyrrole Polymer Transistors Under Aqueous Condition Toward Biosensing Platform

Advanced Materials Technologies, EarlyView.
We are reporting the first‐time investigation of DPP‐based Organic Field‐Effect Transistor (OFET) devices with high‐stability of signal response in both of ambient and aqueous conditions with PBS solution. ABSTRACT Diketopyrrolopyrrole (DPP)–based conjugated polymers show strong promise for electronic applications, including bioelectronic gas sensors ...
Chattarika Khamhanglit, Yudai Hemmi, Ami Ichikawa, YuanTong Gu, Kuniaki Nagamine, Hiroyuki Matsui, Prashant Sonar   +6 more
wiley   +1 more source

Adipose-derived Stem Cell Conditioned Media Extends Survival time of a mouse model of Amyotrophic Lateral Sclerosis [PDF]

, 2015
Adipose stromal cells (ASC) secrete various trophic factors that assist in the protection of neurons in a variety of neuronal death models. In this study, we tested the effects of human ASC conditional medium (ASC-CM) in human amyotrophic lateral ...
Du, Yansheng, Farlow, Martin R., Fontanilla, Christine V., Gu, Huiying, Johnstone, Brian H., Liu, Qingpeng, March, Keith L., Pascuzzi, Robert M., Zhou, Changwei, Zhu, Timothy Z.   +9 more
core   +1 more source

Pathogenic Role of FGFR3 Autoantibodies in Small Fiber Neuropathy

Advanced Science, EarlyView.
Autoantibodies against fibroblast growth factor receptor 3 (FGFR3) are identified as pathogenic drivers of pain in small fiber neuropathy. By binding to sensory neurons in dorsal root ganglia, FGFR3 autoantibodies activate MAPK signaling and induce hyperexcitability and mechanical hypersensitivity, establishing FGFR3 autoantibodies as a therapeutic ...
Lyuba Y. Salih, Nicolas L.A. Dumaire, Clémence Gieré, Erin Vest, Haya Alkhateeb, Christian P. Moritz, Yannick Tholance, Jean‐Philippe Camdessanché, Jean‐Christophe Antoine, Jérôme Honnorat, Jafar Kafaie, Liberty François‐Moutal, Aubin Moutal   +12 more
wiley   +1 more source