Results 61 to 70 of about 265,081 (302)

Enhanced Human Antigen‐Specific B Cell Responses Using In Vitro 3D Tonsil Cultures Containing Stromal Cells

Advanced Healthcare Materials, EarlyView.
We developed a fully human 3D tonsil cell culture system incorporating supportive stromal cells that better sustains and activates immune cells than conventional methods. The model generates stronger, more targeted antibody responses to viral antigens and vaccines, providing a physiologically relevant and entirely human platform for studying immune ...
Maaike V. J. Braham, Marlon de Gast, Liubov Babii, Sabine Kruijer, Theo M. Bestebroer, Mathilde Richard, Mathieu Claireaux, S. Marieke van Ham, Jelle de Wit, Cécile A. C. M. van Els, Anja ten Brinke, Marit J. van Gils   +11 more
wiley   +1 more source

AUV/ASC cooperative survey [PDF]

, 2016
In this paper we describe a solution to perform autonomous surveys taking advantage of a cooperative multivehicle setup. In the proposed configuration, an ASC provides –through an USBL- absolute positioning and communications to an AUV.
Carreras, Marc, Hurtós, Natalia, Palomeras, Narcís   +2 more
core  

Sensorimotor Difficulties Are Associated with the Severity of Autism Spectrum Conditions [PDF]

, 2016
Present diagnostic criteria for autism spectrum conditions (ASC) include social communication and interaction difficulties, repetitive behaviour and movement, and atypical sensory responsivity.
Amaral, American Psychiatric Association, Asperger, Baranek, Bauman, Beery, Ben-Sasson, Bhat, Blakemore, Bo, Bodner, Boyd, Brisson, Brooks, Caminha, Chawarska, Chukoskie, Cummins, Damasio, DeMyer, Di Martino, Dowd, Dunn, Dunn, Estes, Fatemi, Faul, Fitzgibbon, Fournier, Francesca Mann, Glazebrook, Glickstein, Gowen, Gowen, Gowen, Green, Haggard, Hannant, Henderson, Hilton, Iwanaga, Kanner, Kavazi, Kawa, Kern, Kopp, Koziol, Landa, Lane, Larson, Machado, MacNeil, Madsen, Matson, Matsushima, McIntosh, Miller, Milne, Ming, Miyahara, Mostofsky, Nagy, Nazarali, Nyström, Ozonoff, Page, Paton, Paulin, Penelope Hannant, Pierce, Price, Reynolds, Rutter, Rutter, Rutter, Sarah Cassidy, Siaperas, Sparrow, Staples, Stins, Stott, Suzuki, Takahashi, Tavassoli, Tavassoli, Teitelbaum, Teresa Tavassoli, Todorov, Tomchek, Torres, Vandenbroucke, Wechsler, Wechsler, Whyatt, Wolpert, Yeomans   +95 more
core   +3 more sources

CORE: Cholesterol Altered Lipid Nanoparticles for Splenic Expression of mRNA Payloads

Advanced Healthcare Materials, EarlyView.
In this paper researchers introduce CORE LNPs, a new class of lipid nanoparticles engineered to redirect mRNA expression away from the liver and into the spleen, a key immune organ. By combining chemical design with computational tools, they created cholesterol analogs that enable precise spleen‐targeted expression, providing greater applications for ...
Eshan A. Narasipura, Vincent Fung, Rachel VanKeulen‐Miller, Palas B. Tiwade, Owen S. Fenton   +4 more
wiley   +1 more source

Cognition in Males and Females with Autism: Similarities and Differences [PDF]

, 2012
The male bias in autism spectrum conditions (ASC) has led to females with ASC being under-researched. This lack of attention to females could hide variability due to sex that may explain some of the heterogeneity within ASC.
Allison, Carrie, Auyeung, B., Bailey, Anthony J., Baron-Cohen, S., Baron-Cohen, Simon, Bolton, Patrick F., Bullmore, E. T., Carrington, Sarah, Catani, Marco, Chakrabarti, B., Craig, Michael C., Daly, E. M., Deoni, Sean C. L., Ecker, Christine, Happé, Francesca, Henty, Julian, Jezzard, Peter, Johnston, Patrick, Jones, Derek Kenton, Lai, Meng C., Lombardo, M. V., Madden, Anya, Mullins, Diane, Murphy, Clodagh M., Murphy, Declan, Pasco, Greg, Ruigrok, Amber N. V., Sadek, Susan A., Spain, Debbie, Stewart, Rose, Suckling, John, Wheelwright, Sally J., Willia, Steven C.   +32 more
core   +4 more sources

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Three particles in an external trap: Nature of the complete J=0 spectrum [PDF]

, 2002
Three bosonic, spin-polarized atoms in a spherical oscillator potential constitutes the simplest nontrivial Bose-Einstein condensate (BEC). The present paper develops the tools needed to understand the nature of the complete J=0 energy spectrum for this ...
A. Fabrocini, B. D. Esry, B. D. Esry, B. D. Esry, B. D. Esry, C. D. Lin, Chris H. Greene, D. Blume, D. Blume, D. Blume, D. Blume, E. A. Donley, E. Braaten, E. Braaten, E. H. Lieb, E. Nielsen, E. Nielsen, E. P. Gross, E. P. Gross, E. Timmermans, E. Timmermans, F. A. van Abeelen, F. Dalfovo, H. Saito, H. T. C. Stoof, H. W. van der Hart, J. J. Hope, J. Javanainen, J. L. Bohn, J. Macek, K. Góral, L. P. Pitaevskii, M. Greiner, M. Holland, M. Holland, M. J. Davis, M. Mackie, O. Sørensen, P. D. Drummond, P. F. Bedaque, R. A. Duine, R. C. Whitten, R. J. Dodd, S. A. Morgan, S. L. Cornish, V. A. Yurovsky, Y. E. Kim, Y. E. Kim, Y. Kagan, Y. Zhou   +49 more
core   +2 more sources

Resolving Complex Multiscale Structure of Magneto‐ and Electroactive Polymer Composites With an Ionic Liquid

Advanced Materials, EarlyView.
Multiscale ionic liquid segregation into nano‐sized domains in the unconfined amorphous polymer phase and into micron‐sized pores enables a coupled magneto‐ and electroactive responses. ABSTRACT A multiscale understanding of the structure of ionogels – nanoparticle‐free polymer composites incorporating ionic liquids – is essential for enhancing their ...
Andrey Shibaev, Jon Maiz, Viktor Petrenko, Amaia Iturrospe, Josu Fernández Maestu, José María Porro, Mariano Barrado, Laura Casado, Joachim Kohlbrecher, Petr Shvets, Evgeny Modin, Ana Sofia Castro, Andrey Chuvilin, José María De Teresa, Daniela M. Correia, Arantxa Arbe, Senentxu Lanceros‐Méndez   +16 more
wiley   +1 more source

Eldercare services for people with and without a dementia diagnosis: an analysis of Swedish registry data

BMC Health Services Research, 2021
Background The growing number of people living with dementia (PlwD) implies an increase in the demand for eldercare services in Sweden like in many other countries. Few studies have analyzed the use of eldercare services for PlwD.
Atiqur sm-Rahman, Lars-Christer Hydén, Susanne Kelfve   +2 more
doaj   +1 more source

A multicenter experience using adipose-derived mesenchymal stem cell therapy for cats with chronic, non-responsive gingivostomatitis. [PDF]

, 2020
BackgroundThe ability of mesenchymal stem cells (MSCs) to modulate immune responses inspired a series of clinical trials addressing oral mucosal inflammation.
Arzi, Boaz, Battig, Jean, Borjesson, Dori L, Clark, Kaitlin C, Delatorre, Ubaldo, Fiani, Nadine, Fulton, Amy, Lommer, Milinda J, Loscar, Megan R, Peralta, Santiago, Taechangam, Nopmanee, Vapniarsky, Natalia, Walker, Naomi J   +12 more
core   +1 more source