Results 41 to 50 of about 102,781 (311)

Realistic scheme for quantum simulation of $${{\mathbb{Z}}}_{2}$$ Z 2 lattice gauge theories with dynamical matter in (2 + 1)D

Communications Physics, 2023
Gauge fields coupled to dynamical matter are ubiquitous in many disciplines of physics, ranging from particle to condensed matter physics, but their implementation in large-scale quantum simulators remains challenging.
Lukas Homeier, Annabelle Bohrdt, Simon Linsel, Eugene Demler, Jad C. Halimeh, Fabian Grusdt   +5 more
doaj   +1 more source

Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

Acta Neuropathologica, 2019
Brains of Alzheimer’s disease patients are characterized by the presence of amyloid plaques and neurofibrillary tangles, both invariably associated with neuroinflammation.
I. Stancu, Niels Cremers, Hannah Vanrusselt, J. Couturier, Alexandre Vanoosthuyse, S. Kessels, Chritica Lodder, B. Brône, F. Huaux, J. Octave, D. Terwel, I. Dewachter   +11 more
semanticscholar   +1 more source

INT-777 attenuates NLRP3-ASC inflammasome-mediated neuroinflammation via TGR5/cAMP/PKA signaling pathway after subarachnoid hemorrhage in rats.

Brain, behavior, and immunity, 2020
Background: Inflammasome-mediated neuroinflammation plays an important role in the pathogenesis of early brain injury (EBI) following subarachnoid hemorrhage (SAH).
Xiao Hu, Jun Yan, Lei Huang, C. Araujo, Jun Peng, Ling Gao, Shengpeng Liu, Jiping Tang, Gang Zuo, John H. Zhang   +9 more
semanticscholar   +1 more source

The ASC Speck and NLRP3 Inflammasome Function Are Spatially and Temporally Distinct

bioRxiv, 2021
Although considered the ternary inflammasome structure, whether the singular, perinuclear NLRP3:ASC speck is synonymous with the NLRP3 inflammasome is unclear.
Abhinit Nagar, Tabassum Rahman, J. Harton   +2 more
semanticscholar   +1 more source

Using Dance & Movement to Enhance Spatial Awareness Learning [PDF]

Athens Journal of Education, 2020
By accessing creative portions of the brain through dance, Pre-K students can more easily learn math concepts like spatial awareness and critical math knowledge prior to formal assessment in elementary school.
Barbara Ann Temple, Kathryn Bentley, David K. Pugalee, Natalie Blundell, Carlos Miranda Pereyra   +4 more
doaj   +1 more source

Luteolin inhibits NLRP3 inflammasome activation via blocking ASC oligomerization.

Journal of Nutritional Biochemistry, 2021
The NLRP3 inflammasome is a caspase-1 containing multi-protein complex that controls the release of IL-1β and plays important roles in the innate immune response. Since NLRP3 inflammasome is implicated in the pathogenesis of a variety of diseases, it has
M. N. Lee, Youngyoon Lee, Dayong Wu, Munkyong Pae   +3 more
semanticscholar   +1 more source

اثر فعالیت شنا بر محتوای پروتئین‌های AIM2، ASC و Caspase1 بافت هیپوکمپ موش‌های صحرایی نر نژاد ویستار مبتلا به مالتیپل اسکلروزیس [PDF]

مجله دانشکده پزشکی اصفهان
مقاله پژوهشیمقدمه: مالتیپل اسکلروزیس، یک بیماری خودایمنی است که به سیستم عصبی مرکزی آسیب می‌زند و باعث تخریب میلین می‌شود. شنا، به عنوان یک فعالیت ترکیبی هوازی و مقاومتی، می‌تواند تغییرات بافت هیپوکامپ ناشی از (Multiple Sclerosis) MS را تنظیم کند.روش‌ها:
مناالسادات کیمیائی, محمد رمی, روح اله رنجبر   +2 more
doaj   +1 more source

Symmetry-protected Bose-Einstein condensation of interacting hardcore bosons

Communications Physics, 2023
The large practical potential of exotic quantum states is often precluded by their notorious fragility against external perturbations or temperature.
Reja H. Wilke, Thomas Köhler, Felix A. Palm, Sebastian Paeckel   +3 more
doaj   +1 more source

Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome

Cell Death and Disease, 2019
Propofol infusion syndrome (PRIS) is an uncommon life-threatening complication observed most often in patients receiving high-dose propofol. High-dose propofol treatment with a prolonged duration can damage the immune system.
Lingbin Sun, Wei-Qing Ma, Wenli Gao, Yanmei Xing, Lixin Chen, Z. Xia, Zhongjun Zhang, Zhongliang Dai   +7 more
semanticscholar   +1 more source

ASC-Exosomes Ameliorate the Disease Progression in SOD1(G93A) Murine Model Underlining Their Potential Therapeutic Use in Human ALS

International Journal of Molecular Sciences, 2020
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive degeneration of motoneurons. To date, there is no effective treatment available.
R. Bonafede, Ermanna Turano, I. Scambi, A. Busato, Pietro Bontempi, Federica Virla, Lorenzo Schiaffino, P. Marzola, B. Bonetti, R. Mariotti   +9 more
semanticscholar   +1 more source