The NLRP3 Inflammasome as a Novel Therapeutic Target for Cardiac Fibrosis
Jiwen Fan,1 Meng Ren,2 Binay Kumar Adhikari,3 Haodong Wang,1 Yuquan He1 1Department of Cardiology, China-Japan Union Hospital of Jilin University, Changchun, People’s Republic of China; 2Department of Medical Oncology, Jilin Provincial Cancer Hospital ...
Fan J, Ren M, Adhikari BK, Wang H, He Y
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HAND, FOOT AND MOUTH DISEASE: A REVIEW
Background: Hand, foot and mouth disease or HFMD is a common childhood infectious disease mainly caused by coxsackievirus A16 (CVA 16) and enterovirus 71 (EV71). This HFMD disease can spread throughout the world and also cause outbreaks.
Lisa Lailatannur
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Government involvement in high performance sport: An Australian national sporting organisation perspective [PDF]
The purpose of this paper is to examine the relationship between the Australian Sports Commission (ASC) and Summer Olympic National Sporting Organisations (NSOs) to determine the effect the relationship has on Olympic performance outcomes.
Gowthorp, Lisa +2 more
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Impact of high-intensity interval training on ASC inflammasome, lipid profile and their correlation in diabetic rat model [PDF]
In Diabetes (Di) exercise training especially high-intensity interval training (HIIT) reduce blood lipids and improve anti-inflammatory status. In this study, we aimed to investigate the impact of high-intensity interval training on ASC inflammasome ...
Reza Sheikh +2 more
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Background Although many people with dementia need progressive support during their last years of life little is known to what extent they use formal long-term care (LTC).
Atiqur sm-Rahman +3 more
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Iterative focused screening with biological fingerprints identifies selective Asc-1 inhibitors distinct from traditional high throughput screening [PDF]
N-methyl-d-aspartate receptors (NMDARs) mediate glutamatergic signaling that is critical to cognitive processes in the central nervous system, and NMDAR hypofunction is thought to contribute to cognitive impairment observed in both schizophrenia and ...
Amoss, Adam +18 more
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COVID-19 pandemic and the exchange rate movements: evidence from six major COVID-19 hot spots
The study’s primary objective is to unravel the nexus between the COVID-19 crisis and the exchange rate movements in the six major COVID-19 hot spots—Brazil, China, India, Italy, Turkey, and the United Kingdom.
Aamir Jamal, Mudaser Ahad Bhat
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Genetic Programming for Smart Phone Personalisation [PDF]
Personalisation in smart phones requires adaptability to dynamic context based on user mobility, application usage and sensor inputs. Current personalisation approaches, which rely on static logic that is developed a priori, do not provide sufficient ...
Cotillon, Alban +3 more
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The plant disease resistance gene Asc-1 prevents disruption of sphingolipid metabolism during AAL-toxin-induced programmed cell death [PDF]
The nectrotrophic fungus Alternaria alternata f.sp. lycopersici infects tomato plants of the genotype asc/asc by utilizing a host-selective toxin, AAL-toxin, that kills the host cells by inducing programmed cell death.
Hille, J +4 more
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CASPorter: A Novel Inducible Human CASP1/NALP3/ASC Inflammasome Biosensor
Chan Zou,1,2 Jordan A Beard,1 Guoping Yang,2– 4 William E Evans,1 Erik J Bonten1,5 1Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, TN, USA; 2Center for Clinical Pharmacology, The Third Xiangya Hospital, Central ...
Zou C +4 more
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