Results 91 to 100 of about 513,389 (355)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Neuroanatomic Connectivity of the Human Ascending Arousal System Critical to Consciousness and Its Disorders

Journal of Neuropathology and Experimental Neurology, 2012
The ascending reticular activating system (ARAS) mediates arousal, an essential component of human consciousness. Lesions of the ARAS cause coma, the most severe disorder of consciousness.
B. Edlow, E. Takahashi, O. Wu, T. Benner, G. Dai, Li-Hong Bu, P. Grant, D. Greer, S. Greenberg, H. Kinney, R. Folkerth   +10 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Sets in Excess Demand in Ascending Auctions with Unit-Demand Bidders [PDF]

This paper analyzes the problem of selling a number of indivisible items to a set of unitdemand bidders. An ascending auction mechanism called the Excess Demand Ascending Auction (EDAA) is defined.
Andersson, C., Andersson, T.D., Talman, A.J.J.   +2 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

ASCENDING POSTEROLATERAL SCLEROSIS [PDF]

The Journal of Nervous and Mental Disease, 1908
n ...
openaire   +2 more sources

Multi-Unit Open Ascending Price Efficient Auction [PDF]

This paper presents an open ascending price mechanism that allocates efficiently M units of the same good among N bidders with interdependent values The mechanism consists of a number of sequential English auctions with reentry and has the following ...
Sergei Izmalkov
core  

Ascending aorta sample collected during cardiac surgery.

, 2021
Ascending aorta sample collected during cardiac surgery.
Marie-Catherine Morgant (11426532), Alexandre Cochet (87005), Alain Lalande (87007), Siyu Lin (5545016), Chloé Bernard (11426538), Diana Marin-Castrillon (11426535), Aline Laubriet (11426541), Olivier Bouchot (5875043)   +7 more
core   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Reassessment of the structural basis of the ascending arousal system

The Journal of comparative neurology, 2011
The “ascending reticular activating system” theory proposed that neurons in the upper brainstem reticular formation projected to forebrain targets that promoted wakefulness.
P. Fuller, D. Sherman, Nigel P. Pedersen, C. Saper, J. Lu   +4 more
semanticscholar   +1 more source