Results 91 to 100 of about 182,211 (308)
CYP3A5 genetic variability influences sildenafil and metabolite in pulmonary hypertension
British Journal of Clinical Pharmacology, EarlyView.Aim Interindividual variability in sildenafil response among pulmonary hypertension patients (PH) may be influenced by CYP3A5 polymorphisms. CYP3A5*3 allele reduces CYP3A5 activity and affects sildenafil metabolism. This study investigated the associations between CYP3A5 genotype and plasma concentrations of sildenafil and N‐desmethyl sildenafil, as ...
Pranisa Wongwien +7 more
wiley +1 more source
The Epidemiology of Ascites in a Multi‐Ethnic Asian Population
JGH OpenIntroduction Ascites is a common condition seen by clinicians in secondary care. Data on the epidemiology of ascites in Asians is lacking. Methodology A retrospective case record review was performed in this large, referral institution between January ...
Ram Prasad Sinnanaidu +5 more
doaj +1 more source
Journal of Ovarian Research, 2012 Background Resistance to apoptosis is a major problem in ovarian cancer and correlates with poor prognosis. Osteoprotegerin (OPG) is a secreted factor in malignant ascites and acts as a decoy receptor for receptor activator of NF-κB ligand (RANKL) and ...
Lane Denis +3 more
doaj +1 more source
Review of catumaxomab in the treatment of malignant ascites [PDF]
, 2010 Martin SebastianDepartment of Internal Medicine III, Hematology, Medical Oncology, and Pneumology, University Medical Center of the Johannes Gutenberg University, Mainz, GermanyAbstract: Malignant ascites is frequently found with various solid tumors ...
Martin Sebastian, null Sebastian
core +1 more source
Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9
Cytoskeleton, EarlyView.ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook +2 more
wiley +1 more source
Cytometry Part B: Clinical Cytometry, EarlyView.Abstract Accurate quantification of chimeric antigen receptor (CAR) T cells is essential for monitoring post‐infusion CART expansion and persistence and for real‐time clinical decision‐making. Multiparameter flow cytometry (MFC) enables rapid, live‐cell detection with absolute quantification and concurrent immunophenotypic characterization. This review
Jianhua Ling, Wei Wang, Sa A. Wang
wiley +1 more source
Chylous Ascites after Excision of a Choledochal Cyst in a Child
, 2011 We report a case of chylous ascites developing 2 weeks, after excision of a choledochal cyst with a Roux-en-Y hepaticojejunostomy. Despite the failure of the initial attempts to resolve the chylous ascites by fasting, subsequently, we successfully ...
黃俊傑;蔡明憲;賴鴻緖 +1 more
core +1 more source
Ascites, pleural, and pericardial effusion in primary hypothyroidism: a rare case report
, 2023 Hypothyroidism is caused by a deficiency of thyroid hormones and is a common endocrine disorder worldwide. It can affect nearly every organ, resulting in multiple clinical manifestations. Ascites, pleural effusion, and pericardial effusion, although less
Mogildea, Mihail +4 more
core +1 more source