Results 71 to 80 of about 182,211 (308)
Deubiquitination of Vangl by USP6 and USP32 Regulates Planar Cell Polarity Signaling
Advanced Science, EarlyView.Compartment‐specific deubiquitination controls Vangl dosage and planar cell polarity signaling. USP6 and USP32 regulate distinct subcellular pools of Vangl by removing distinct ubiquitin modifications from Vangl proteins. This regulatory mechanism safeguards PCP‐dependent embryonic morphogenesis, while aberrant USP32‐dependent stabilization of VANGL ...
Fangzi Zha +13 more
wiley +1 more source
, 2020 The majority of women with recurrent ovarian cancer (OvCa) develop malignant ascites with volumes that can reach > 2 L. The resulting elevation in intraperitoneal pressure (IPP), from normal values of 5 mmHg to as high as 22 mmHg, causes striking changes
Carlysa Oyama (17548869) +9 more
core +1 more source
Annals of Gastroenterological Surgery, EarlyView.This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi +8 more
wiley +1 more source
Interferon-gamma in ascites could be a predictive biomarker of outcome in ovarian carcinoma
, 2017 Objective. The ovarian cancer-associated ascites is an ideal material for evaluating the interaction between the host immune system and cancer cells in the tumor micro-environment.
Chen, Yu-Li;Cheng, Wen-Fang;Chang, Ming-Cheng;Lin, Han-Wei;Huang, Ching-Ting;Chien, Chung-Liang;Chen, Chi-An +1 more
core +1 more source
Ultrasound, 2016 The excess accumulation of intra-peritoneal fluid, referred to as ascites, is an important clue that points to a significant underlying illness. This may be due to a pathological event within the peritoneal cavity or secondary to an underlying systemic condition.
Velauthan, Rudralingam +2 more
openaire +2 more sources
Annals of Gastroenterological Surgery, EarlyView.This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura +9 more
wiley +1 more source
Scientific ReportsPreliminary work has shown that portal hypertension plays a key role for the prognosis in patients with hepatocellular carcinoma (HCC) undergoing transarterial chemoembolization (TACE).
Lukas Müller +11 more
doaj +1 more source
Placing a lumen-apposing metal stent despite ascites: feasibility and safety
VideoGIE, 2020 Background and Aims: Placing a lumen-apposing metal stent (LAMS) through ascites carries serious risks, including death from leakage around the LAMS and failure to create a mature fistula between the 2 lumens.
Shayan Irani, MD
doaj +1 more source
Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone +11 more
wiley +1 more source